Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 4/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 4/20 | 0.37 |
| ▸ | PRKACA | P17612 | 4/20 | 0.37 |
| ▸ | CLK2 | P49760 | 4/20 | 0.37 |
| ▸ | GSK3A | P49840 | 4/20 | 0.37 |
| ▸ | GSK3B | P49841 | 4/20 | 0.37 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.37 |
| ▸ | MAP4K2 | Q12851 | 4/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 4/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.37 |
| ▸ | PDPK1 | O15530 | 4/20 | 0.37 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.37 |
| ▸ | TAOK1 | Q7L7X3 | 3/20 | 0.37 |
| ▸ | NTRK3 | Q16288 | 3/20 | 0.37 |
| ▸ | CDC7 | O00311 | 3/20 | 0.37 |
| ▸ | CHUK | O15111 | 3/20 | 0.37 |
| ▸ | DYRK3 | O43781 | 3/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.37 |
| ▸ | PRKCG | P05129 | 3/20 | 0.37 |
| ▸ | LCK | P06239 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17367347 | 0.80 | — | — | |
| SCHEMBL17367341 | 0.74 | TTBK1 (0.39) | MAPTKMT2AALDH1A1TDP1 | |
| SCHEMBL1272493 | 0.69 | DRD4 (0.30) | — | |
| SCHEMBL17367351 | 0.67 | SMN1; SMN2 (0.35) | CDK1CDK2MAPK1MAPTKDM4E | |
| SCHEMBL3388862 | 0.65 | KDM4E (0.40) | PRKD3MAP4K4PRKACACLK2GSK3A | |
| SCHEMBL2938674 | 0.65 | JAK2 (0.54) | PRKD3MAP4K4PRKACACLK2GSK3A | |
| SCHEMBL13828076 | 0.64 | ALDH1A1 (0.46) | MAPK1DPP4KDM4EALDH1A1CYP1A2 | |
| Biphenyl SCHEMBL19716178 | 0.63 | MAP4K4 (0.44) | MAP4K4PDPK1CDC7LIMK1DPP4 | |
| SCHEMBL17367387 | 0.63 | CA12 (0.33) | PRKACAPDPK1CDK2MARK3PRKCD | |
| Hydrochloric Acid SCHEMBL17364313 | 0.62 | CA12 (0.35) | PRKACAPDPK1CDK2MARK3PRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150376219-A1 | Selective Preparations of Purine Nucleosides and Nucleotides: Reagents and Methods | ZHONG MINGHONG (US) | 2015-12-31 | — | — | US | disclosed |
| US-20150376219-A1 | Selective Preparations of Purine Nucleosides and Nucleotides: Reagents and Methods | ZHONG MINGHONG (US) | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376219-A1 | Selective Preparations of Purine Nucleosides and Nucleotides: Reagents and Methods | PNP, ATIC, NT5C3B | PRKD3 716/4885MAP4K4 2337/4885PRKACA 681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.