Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.41 |
| ▸ | NT5E | P21589 | 3/20 | 0.35 |
| ▸ | POLA1 | P09884 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17367358 | 1.00 | PNP (0.41) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17367367 | 1.00 | PNP (0.41) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17367383 | 0.86 | PNP (0.43) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17367348 | 0.86 | PNP (0.43) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17367346 | 0.86 | PNP (0.43) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17367365 | 0.83 | PNP (0.43) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17367344 | 0.83 | PNP (0.43) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17367345 | 0.83 | PNP (0.43) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL10326713 | 0.76 | LMNA (0.51) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL17364320 | 0.76 | YTHDC1 (0.41) | PNPPDE4DSMN1; SMN2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150376219-A1 | Selective Preparations of Purine Nucleosides and Nucleotides: Reagents and Methods | ZHONG MINGHONG (US) | 2015-12-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150376219-A1 | Selective Preparations of Purine Nucleosides and Nucleotides: Reagents and Methods | PNP, ATIC, NT5C3B | PNP 1/4885LMNA 1004/4885TP53 4344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.