SCHEMBL17367991

SCHEMBL17367991

CCCc1ccc(-c2ccc(-c3ccc(OC(F)(F)c4cc(F)c(F)c(F)c4)c(F)c3)c(F)c2)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CTSK P43235 2/20 0.37
CTSL P07711 1/20 0.37
CTSS P25774 1/20 0.37
PPARD Q03181 3/20 0.34
NAAA Q02083 2/20 0.34
GABRA1 P14867 3/20 0.32
GABRB2 P47870 3/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
ALOX5 P09917 1/20 0.31
ALOX5AP P20292 4/20 0.31
FEN1 P39748 4/20 0.31
RORC P51449 3/20 0.31
APP P05067 1/20 0.30
RORA P35398 1/20 0.30
NR1H4 Q96RI1 1/20 0.30
KDM4E B2RXH2 1/20 0.30
NPC1 O15118 1/20 0.30
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17368009 0.96 CTSK (0.35) CTSKCTSLCTSSPPARDNAAA
SCHEMBL17367989 0.93 CTSK (0.37) CTSKCTSLCTSSNAAA
SCHEMBL17367992 0.90 CTSL (0.34) CTSKCTSLCTSSPPARDALOX5AP
SCHEMBL17368000 0.87 CTSL (0.34) CTSKCTSLCTSSPPARD
SCHEMBL17368019 0.87 CTSK (0.36) CTSKCTSLCTSSPPARDNAAA
SCHEMBL17367993 0.86 CTSK (0.35) CTSKCTSLCTSSPPARDNAAA
SCHEMBL17365975 0.85 CTSL (0.34) CTSKCTSLCTSSPPARDALOX5AP
SCHEMBL17368028 0.85 CTSL (0.36) CTSKCTSLCTSSRORC
SCHEMBL17368008 0.84 APP (0.34) CTSKCTSLCTSSPPARDALOX5AP
SCHEMBL17365839 0.84 ALOX5AP (0.38) CTSKCTSLCTSSPPARDNAAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10023799-B2 Liquid crystal compound, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2018-07-17 US disclosed
US-20150376504-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2015-12-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10023799-B2 Liquid crystal compound, liquid crystal composition and liquid crystal display device PIEZO1, ROCK1, RCC1 CTSK 1913/4885CTSL 2885/4885CTSS 2894/4885
US-20150376504-A1 LIQUID CRYSTAL COMPOUND, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE PIEZO1, ROCK1, RCC1 CTSK 1913/4885CTSL 2885/4885CTSS 2894/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.