Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 4/20 | 0.41 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.41 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.32 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.32 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | DDO | Q99489 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13397530 | 0.98 | GABRA1 (0.43) | GABRA1GABRB2HTR1ATP53MEN1 | |
| Hydrochloric Acid SCHEMBL3143919 | 0.71 | CYP2A6 (0.36) | MEN1CYP1A2KMT2ASLC22A2SLC22A1 | |
| Hydrochloric Acid SCHEMBL29672576 | 0.71 | GABRA1 (0.34) | GABRA1GABRB2HTR1ADRD2DRD4 | |
| SCHEMBL5159445 | 0.69 | CYP2A6 (0.38) | MEN1CYP1A2KMT2ASLC22A2SLC22A1 | |
| SCHEMBL3238496 | 0.66 | GABRA1 (0.57) | GABRA1GABRB2CYP1A2CYP2D6CYP2C19 | |
| SCHEMBL25425763 | 0.62 | GABRA1 (0.58) | GABRA1GABRB2TP53CYP2D6MAPT | |
| SCHEMBL36294 | 0.62 | GABRA1 (0.58) | GABRA1GABRB2TP53CYP2D6MAPT | |
| SCHEMBL29390847 | 0.62 | GABRA1 (0.58) | GABRA1GABRB2TP53CYP2D6MAPT | |
| SCHEMBL599099 | 0.61 | GABRA1 (0.57) | GABRA1GABRB2HTR1ATAAR1TP53 | |
| SCHEMBL245773 | 0.61 | GABRA1 (0.57) | GABRA1GABRB2HTR1ATAAR1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0962923-B1 | Information recording medium and novel oxonol compound | FUJIFILM CORP (JP) | 2011-11-16 | — | — | EP | disclosed |
| US-20110263215-A1 | Method and Device in Over-the-Air Test Environment | TELEFONAKTIEBOLAGET LM ERICSSON (PUBL) (SE) | 2011-10-27 | — | — | US | disclosed |
| US-6646132-B2 | Optical recording media | FUJI PHOTO FILM CO., LTD. (JP) | 2003-11-11 | — | — | US | disclosed |
| US-20020009669-A1 | Information recording medium and novel oxonol compound | FUJIFILM CORPORATION (JP) | 2002-01-24 | — | — | US | disclosed |
| US-6225024-B1 | METHINE OXONOL DYE | FUJI PHOTO FILM CO., LTD. (JP) | 2001-05-01 | — | — | US | disclosed |
| EP-0962923-A1 | Information recording medium and novel oxonol compound | FUJI PHOTO FILM CO., LTD. (JP) | 1999-12-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020009669-A1 | Information recording medium and novel oxonol compound | CACNA1S, KCNN1, KCNN2 | GABRA1 2624/4885GABRB2 2611/4885HTR1A 746/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.