Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 3/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | ANPEP | P15144 | 2/20 | 0.32 |
| ▸ | DPP4 | P27487 | 2/20 | 0.32 |
| ▸ | NPEPPS | P55786 | 2/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD4 | P21917 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL673215 | 0.84 | DAO (0.31) | — | |
| SCHEMBL1751108 | 0.78 | — | — | |
| SCHEMBL28045651 | 0.72 | GABRA1 (0.46) | GABRA1GABRB2CRHBPCRHR2ANPEP | |
| Hydrochloric Acid SCHEMBL1737122 | 0.71 | GABRA1 (0.41) | GABRA1GABRB2HTR1ADRD2DRD4 | |
| Hydrochloric Acid SCHEMBL28358971 | 0.69 | — | — | |
| SCHEMBL13397530 | 0.69 | GABRA1 (0.43) | GABRA1GABRB2HTR1ADRD2DRD4 | |
| SCHEMBL820123 | 0.68 | MEN1 (0.31) | — | |
| SCHEMBL11077561 | 0.67 | IDO1 (0.46) | — | |
| Hydrochloric Acid SCHEMBL28617768 | 0.67 | NPEPPS (0.32) | GABRA1GABRB2CRHBPCRHR2ANPEP | |
| Hydrochloric Acid SCHEMBL28358970 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113045533-B | Synthetic method of cyclic carbonate | 南京工业大学 | 2022-10-21 | — | — | CN | disclosed |
| CN-114644661-A | Imidazole carbene iron complex and application thereof | 北京服装学院 | 2022-06-21 | — | — | CN | disclosed |