Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.60 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.60 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.60 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.57 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.57 |
| ▸ | HNF4A | P41235 | 1/20 | 0.51 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.51 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.50 |
| ▸ | FGFR2 | P21802 | 3/20 | 0.50 |
| ▸ | FGFR4 | P22455 | 3/20 | 0.50 |
| ▸ | FGFR3 | P22607 | 3/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22256436 | 0.91 | FGFR1 (0.57) | MAPTTSHRMEN1KMT2AHTT | |
| SCHEMBL22256427 | 0.89 | FGFR1 (0.56) | MAPTTSHRMEN1KMT2AHTT | |
| SCHEMBL4827474 | 0.86 | HNF4A (0.66) | MAPTTSHRMEN1KMT2AHTT | |
| SCHEMBL22256425 | 0.86 | SLC6A3 (0.65) | MAPTTSHRMEN1KMT2AHTT | |
| SCHEMBL31109161 | 0.86 | SLC6A3 (0.65) | MAPTTSHRMEN1KMT2AHTT | |
| SCHEMBL22256434 | 0.86 | SLC6A3 (0.65) | MAPTTSHRMEN1KMT2AHTT | |
| SCHEMBL1775832 | 0.85 | SLC6A3 (0.74) | MAPTTSHRMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL27843639 | 0.85 | SLC6A3 (0.74) | MAPTTSHRMEN1KMT2AHTT | |
| SCHEMBL15008455 | 0.84 | MYC (0.61) | MAPTTSHRMEN1KMT2AHTT | |
| Bicarbonate SCHEMBL6812921 | 0.84 | SLC6A3 (0.63) | MAPTTSHRMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10087205-B2 | Metal organic frameworks comprising a plurality of SBUS with different metal ions and/or a plurality of organic linking ligands with different functional groups | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2018-10-02 | — | — | US | disclosed |
| US-20170101429-A1 | METAL ORGANIC FRAMEWORKS COMPRISING A PLURALITY OF SBUS WITH DIFFERENT METAL IONS AND/OR A PLURALITY OF ORGANIC LINKING LIGANDS WITH DIFFERENT FUNCTIONAL GROUPS | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-04-13 | — | — | US | disclosed |
| WO-2015195179-A2 | METAL ORGANIC FRAMEWORKS COMPRISING A PLURALITY OF SBUS WITH DIFFERENT METAL IONS AND/OR A PLURALITY OF ORGANIC LINKING LIGANDS WITH DIFFERENT FUNCTIONAL GROUPS. | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170101429-A1 | METAL ORGANIC FRAMEWORKS COMPRISING A PLURALITY OF SBUS WITH DIFFERENT METAL IONS AND/OR A PLURALITY OF ORGANIC LINKING LIGANDS WITH DIFFERENT FUNCTIONAL GROUPS | EPCAM, SOD1, SBDS | MAPT 1623/4885TSHR 4014/4885MEN1 3390/4885 |
| US-10087205-B2 | Metal organic frameworks comprising a plurality of SBUS with different metal ions and/or a plurality of organic linking ligands with different functional groups | EPCAM, SOD1, SBDS | MAPT 1623/4885TSHR 4014/4885MEN1 3390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.