Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019073 | 0.85 | NPC1 (0.33) | NPC1TSHRALDH1A1KDM4EL3MBTL1 | |
| SCHEMBL16004864 | 0.81 | TSHR (0.50) | NPC1TSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL498003 | 0.80 | TSHR (0.55) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| Potassium SCHEMBL30901224 | 0.79 | TSHR (0.48) | NPC1TSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL11092121 | 0.77 | CES2 (0.52) | NPC1LMNAALDH1A1POLBL3MBTL1 | |
| SCHEMBL28846633 | 0.77 | NPC1 (0.43) | NPC1TSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL15611971 | 0.76 | SLC6A3 (0.51) | TSHRLMNAALDH1A1HSD17B10CFTR | |
| SCHEMBL19638940 | 0.76 | TSHR (0.67) | NPC1TSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL17607318 | 0.76 | NPC1 (0.40) | NPC1TSHRLMNAALDH1A1HSD17B10 | |
| SCHEMBL30778085 | 0.74 | LMNA (0.62) | NPC1TSHRLMNAALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024027792-A1 | PROTEIN KINASE DEGRADING AGENT, MEDICAMENT AND USE | SHENZHEN NEWDEL BIOTECH CO., LTD. (CN) | 2024-02-08 | — | — | WO | disclosed |
| WO-2015197028-A1 | COMPOUNDS AS HEPATITIS C VIRUS (HCV) INHIBITORS AND USES THEREOF IN MEDICINE | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2015-12-30 | — | — | WO | disclosed |