Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21045666 | 0.74 | QDPR (0.35) | QDPRBRPF1 | |
| SCHEMBL17376304 | 0.71 | PLAT (0.36) | — | |
| SCHEMBL25385174 | 0.70 | NR1H2 (0.32) | — | |
| SCHEMBL27233080 | 0.70 | NAMPT (0.33) | QDPR | |
| SCHEMBL3666130 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL21045793 | 0.67 | NR1H2 (0.32) | QDPR | |
| SCHEMBL15057744 | 0.66 | GABRP (0.31) | — | |
| SCHEMBL18398429 | 0.65 | ADORA1 (0.31) | — | |
| SCHEMBL5492828 | 0.65 | PREP (0.36) | — | |
| SCHEMBL3664878 | 0.64 | HTR2C (0.35) | QDPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160961-A2 | SMALL MOLECULE AGONISTS OF NEUROTENSIN RECEPTOR 1 | Sanford-Burnham Medical Research Institute (US) | 2017-05-03 | — | — | EP | disclosed |
| WO-2015200534-A2 | SMALL MOLECULE AGONISTS OF NEUROTENSIN RECEPTOR 1 | SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) | 2015-12-30 | — | — | WO | disclosed |