Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | HSPD1 | P10809 | 2/20 | 0.60 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.60 |
| ▸ | HSPE1 | P61604 | 2/20 | 0.60 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.60 |
| ▸ | AR | P10275 | 1/20 | 0.60 |
| ▸ | TSHR | P16473 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | USP2 | O75604 | 1/20 | 0.60 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.60 |
| ▸ | ESR1 | P03372 | 1/20 | 0.60 |
| ▸ | TST | Q16762 | 1/20 | 0.60 |
| ▸ | VDR | P11473 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23192305 | 1.00 | ALDH1A1 (0.60) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1896384 | 1.00 | ALDH1A1 (0.60) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL16473176 | 1.00 | ALDH1A1 (0.60) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1896385 | 1.00 | ALDH1A1 (0.60) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1892774 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1892773 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1898177 | 0.88 | ALDH1A1 (0.50) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL8946861 | 0.82 | MEN1 (0.68) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL1894983 | 0.82 | MEN1 (0.68) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 | |
| SCHEMBL8946866 | 0.82 | MEN1 (0.68) | ALDH1A1ALOX15CYP3A4LMNAHSPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170153254-A1 | ASSAYS FOR VITAMIN D EPIMERS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2017-06-01 | — | — | US | disclosed |
| US-20170121426-A1 | BINDING PARTNERS SPECIFIC FOR VITAMIN D EPIMERS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2017-05-04 | — | — | US | disclosed |
| US-20170114012-A1 | COMPOSITIONS RELATING TO VITAMIN D | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2017-04-27 | — | — | US | disclosed |
| WO-2015200180-A1 | COMPOSITIONS RELATING TO VITAMIN D | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015200186-A1 | BINDING PARTNERS SPECIFIC FOR VITAMIN D EPIMERS IN VITAMIN D ASSAYS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015200182-A1 | BINDING PARTNERS SPECIFIC FOR VITAMIN D EPIMERS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2015-12-30 | — | — | WO | disclosed |
| WO-2015200178-A1 | ASSAYS FOR VITAMIN D EPIMERS | SIEMENS HEALTHCARE DIAGNOSTICS INC. (US) | 2015-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170114012-A1 | COMPOSITIONS RELATING TO VITAMIN D | VDR, CYP24A1, CYP2R1 | ALDH1A1 1241/4885ALOX15 256/4885CYP3A4 1049/4885 |
| US-20170121426-A1 | BINDING PARTNERS SPECIFIC FOR VITAMIN D EPIMERS | GC, CYP24A1, VDR | ALDH1A1 3253/4885ALOX15 1536/4885CYP3A4 900/4885 |
| US-20170153254-A1 | ASSAYS FOR VITAMIN D EPIMERS | CYP24A1, VDR, GC | ALDH1A1 2308/4885ALOX15 1125/4885CYP3A4 158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.