Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 2/20 | 0.48 |
| ▸ | CTSB | P07858 | 2/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | AKT1 | P31749 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17384424 | 0.92 | CTSL (0.50) | CTSLCTSBCTSSMAPK1NPC1 | |
| SCHEMBL19193386 | 0.88 | CTSL (0.46) | CTSLCTSBCTSSMAPK1NPC1 | |
| SCHEMBL19567156 | 0.87 | CTSL (0.48) | CTSLCTSBCTSSMAPK1NPC1 | |
| SCHEMBL19567152 | 0.86 | CTSL (0.49) | CTSLCTSBCTSSMAPK1NPC1 | |
| SCHEMBL19567145 | 0.84 | CTSL (0.55) | CTSLCTSBCTSSLMNAAKT1 | |
| SCHEMBL20187564 | 0.83 | AKT1 (0.60) | CTSLCTSBCTSSNPC1LMNA | |
| SCHEMBL4108739 | 0.82 | LMNA (0.53) | MAPK1NPC1LMNAALOX15TSHR | |
| SCHEMBL28379336 | 0.80 | NPC1 (0.45) | CTSLCTSBCTSSMAPK1NPC1 | |
| SCHEMBL9844474 | 0.80 | MAPK1 (0.60) | MAPK1NPC1LMNAALOX15TSHR | |
| SCHEMBL16620311 | 0.80 | ALOX5 (0.46) | CTSLCTSBCTSSMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9937259-B2 | Abiraterone derivatives and non-covalent complexes with albumin | ZHUHAI BEIHAI BIOTECH CO., LTD. (CN) | 2018-04-10 | — | — | US | disclosed |
| US-20170216443-A1 | ABIRATERONE DERIVATIVES AND NON-COVALENT COMPLEXES WITH ALBUMIN | ZHUHAI BEIHAI BIOTECH CO., LTD. (CN) | 2017-08-03 | — | — | US | disclosed |
| US-20170216443-A1 | ABIRATERONE DERIVATIVES AND NON-COVALENT COMPLEXES WITH ALBUMIN | ZHUHAI BEIHAI BIOTECH CO., LTD. (CN) | 2017-08-03 | — | — | US | disclosed |
| WO-2015200837-A1 | ABIRATERONE DERIVATIVES AND NON-COVALENT COMPLEXES WITH ALBUMIN | FL THERAPEUTICS LLC (US) | 2015-12-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170216443-A1 | ABIRATERONE DERIVATIVES AND NON-COVALENT COMPLEXES WITH ALBUMIN | CYP17A1, SHBG, CYP19A1 | CTSL 1481/4885CTSB 1589/4885CTSS 967/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.