Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | CHAT | P28329 | 1/20 | 0.33 |
| ▸ | BLVRB | P30043 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.33 |
| ▸ | GNG2 | P59768 | 1/20 | 0.32 |
| ▸ | GNB1 | P62873 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3358989 | 0.97 | MEN1 (0.33) | MEN1USP2KMT2ATHRBCDK2 | |
| SCHEMBL6415591 | 0.87 | MEN1 (0.34) | MEN1USP2KMT2ATHRBCDK2 | |
| SCHEMBL6037101 | 0.86 | SMAD3 (0.32) | GNG2GNB1 | |
| SCHEMBL29838713 | 0.86 | MEN1 (0.39) | MEN1USP2KMT2ATHRBCDK2 | |
| SCHEMBL16118 | 0.86 | MEN1 (0.39) | MEN1USP2KMT2ATHRBCDK2 | |
| SCHEMBL29353753 | 0.86 | MEN1 (0.39) | MEN1USP2KMT2ATHRBCDK2 | |
| SCHEMBL345532 | 0.86 | GNG2 (0.40) | MEN1USP2KMT2ATHRBCDK2 | |
| SCHEMBL29831001 | 0.86 | GNG2 (0.40) | MEN1USP2KMT2ATHRBCDK2 | |
| SCHEMBL6823049 | 0.81 | RECQL (0.43) | MEN1USP2KMT2ATHRBCDK2 | |
| SCHEMBL203192 | 0.81 | GNG2 (0.43) | MEN1USP2KMT2ATHRBCDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3443353-B1 | METHODS AND KITS FOR THE DIAGNOSIS AND RISK STRATIFICATION OF PATIENTS WITH ISCHEMIA | FUNDACIO INST DE RECERCA DE LHOSPITAL DE LA SANTA CREU I SANT PAU (ES) | 2024-03-13 | — | — | EP | disclosed |
| EP-3232200-A1 | METHODS AND KITS FOR THE DIAGNOSIS AND RISK STRATIFICATION OF PATIENTS WITH ISCHEMIA | Institut Catalá De Ciencies Cardiovasculars (ICCC) (ES) | 2017-10-18 | — | — | EP | disclosed |
| EP-2400304-A1 | Method for the characterization of intermolecular interactions | Centro de Investigación Cooperativa En Biomateriales ( CIC biomaGUNE) (ES) | 2011-12-28 | — | — | EP | disclosed |