SCHEMBL203192

SCHEMBL203192

O=C(O)c1ccc2c(c1)C(=O)OC21c2cc(Cl)c(O)c(Cl)c2Oc2c1cc(Cl)c(O)c2Cl

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GNG2 P59768 1/20 0.43
GNB1 P62873 1/20 0.43
RECQL P46063 4/20 0.43
TDP1 Q9NUW8 4/20 0.43
MEN1 O00255 3/20 0.43
BLM P54132 3/20 0.43
KMT2A Q03164 3/20 0.43
THRB P10828 3/20 0.43
ACE2 Q9BYF1 2/20 0.43
PRMT1 Q99873 2/20 0.43
USP2 O75604 1/20 0.43
CDK2 P24941 1/20 0.43
CHAT P28329 1/20 0.43
BLVRB P30043 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
L3MBTL1 Q9Y468 1/20 0.43
GAA P10253 1/20 0.42
PKM P14618 1/20 0.42
FTO Q9C0B1 7/20 0.40
SMAD3 P84022 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6823049 0.91 RECQL (0.43) GNG2GNB1RECQLTDP1MEN1
SCHEMBL202968 0.90 GNG2 (0.43) GNG2GNB1RECQLTDP1MEN1
SCHEMBL29831001 0.86 GNG2 (0.40) GNG2GNB1RECQLTDP1MEN1
SCHEMBL345532 0.86 GNG2 (0.40) GNG2GNB1RECQLTDP1MEN1
SCHEMBL6415591 0.83 MEN1 (0.34) GNG2GNB1RECQLTDP1MEN1
SCHEMBL498286 0.83 MEN1 (0.61) GNG2GNB1RECQLTDP1MEN1
SCHEMBL29486978 0.83 MEN1 (0.61) GNG2GNB1RECQLTDP1MEN1
SCHEMBL7589676 0.83 SMAD3 (0.37) GNG2GNB1RECQLTDP1MEN1
SCHEMBL3717351 0.82 SMAD3 (0.45) GNG2GNB1RECQLTDP1MEN1
SCHEMBL20526266 0.81 SMAD3 (0.49) GNG2GNB1RECQLTDP1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1175 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11779896-B2 Magnetic-optical composite nanostructure KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2023-10-10 US claimed
EP-3514177-B1 ANTIBODY SPECIFICALLY BINDING TO PD-1 AND FUNCTIONAL FRAGMENT THEREOF Beijing hanmi pharm co ltd (CN) 2023-07-26 EP claimed
US-20220146431-A1 REAGENTS AND METHODS FOR DETECTING INFECTIOUS DISEASES IONICA SCIENCES 2022-05-12 US claimed
EP-3514176-B1 ANTIBODY SPECIFICALLY BINDING TO IL-17A AND FUNCTIONAL FRAGMENT THEREOF BEIJING HANMI PHARMACEUTICAL CO LTD (CN) 2021-12-15 EP claimed
EP-2596119-B1 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS ASTELLAS INST FOR REGENERATIVE MEDICINE (US) 2021-04-28 EP claimed
CN-112391347-A Magneto-optical composite nanostructures, methods of making same, and methods of detecting, separating, or imaging analytes 高丽大学校产学协力团 2021-02-23 CN claimed
US-20210046443-A1 MAGNETIC-OPTICAL COMPOSITE NANOSTRUCTURE KOREA UNIVERSITY RESEARCH AND BUSINESS FOUNDATION (KR) 2021-02-18 US claimed
US-20200385790-A1 HETERODIMERIC CORE-SHELL NANOPARTICLE IN WHICH RAMAN-ACTIVE MOLECULES ARE LOCATED AT A BINDING PORTION OF A NANOPARTICLE HETERODIMER, USE THEREOF, AND METHOD FOR PREPARING SAME KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2020-12-10 US claimed
EP-2371927-B1 Fluorescent dye compounds, conjugates and uses thereof LIFE TECHNOLOGIES CORP (US) 2020-03-11 EP claimed
US-20190256588-A1 ANTIBODY SPECIFICALLY BINDING TO IL-17A AND FUNCTIONAL FRAGMENT THEREOF BEIJING HANMI PHARM. CO., LTD. (CN) 2019-08-22 US claimed
US-20060228357-A1 dimerization and docking domains; fusion proteins IBC PHARMACEUTICALS, INC. 2006-10-12 US claimed
US-20060063734-A1 4,7-dichlorofluorescein dyes as molecular probes APPLERA CORPORATION (US) 2006-03-23 US claimed
US-20050084870-A1 4,7-dichlorofluorescein dyes as molecular probes APPLERA CORPORATION (US) 2005-04-21 US claimed
US-6504024-B2 Useful as substrates for polymerase enzymes; used in preparing fluorescently-labeled nucleotides useful as substrates for thermostable polymerases PE CORPORATION (NY) 2003-01-07 US claimed
EP-0777749-B1 COUPLED AMPLIFICATION AND LIGATION METHOD PE CORP NY (US) 2002-10-30 EP claimed
US-20020081616-A1 4,7-dichlorofluorescein dyes as molecular probes THE PERKIN-ELMER CORPORATION 2002-06-27 US claimed
JP-3102800-B2 2000-10-23 JP claimed
US-6130073-A DETECTING A TARGET NUCLEOTIDE SEQUENCES IN A SAMPLE; AMPLIFYING TARGET NUCLEOTIDE SEQUENCES BY PRIMER EXTENSION, LIGATING OLIGONUCLEOTIDE PROBES AND DETECTING LIGATION PRODUCTS PERKIN-ELMER CORP., APPLIED BIOSYSTEMS DIVISION (US) 2000-10-10 US claimed
US-5912148-A DETECTION OF POLYNUCLEOTIDE IN SAMPLE BY POLYMERASE CHAIN REACTION AND LIGATION OF OLIGONUCLEOTIDE PROBES WHICH HYBRIDIZE TO AMPLIFICATION PRODUCT, DETECTION OF LIGATION PRODUCT IN ONE REACTION VESSEL PERKIN-ELMER CORPORATION APPLIED BIOSYSTEMS (US) 1999-06-15 US claimed
WO-1996006190-A2 COUPLED AMPLIFICATION AND LIGATION METHOD PERKIN-ELMER CORPORATION (US) 1996-02-29 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060063734-A1 4,7-dichlorofluorescein dyes as molecular probes SPAG5, SPG11, SPIN4 GNG2 3691/4885GNB1 3518/4885RECQL 193/4885
US-20050084870-A1 4,7-dichlorofluorescein dyes as molecular probes DCLRE1B, DCTD, DDB1 GNG2 3164/4885GNB1 2951/4885RECQL 226/4885
US-20020081616-A1 4,7-dichlorofluorescein dyes as molecular probes SPAG5, SPG11, SPIN4 GNG2 3726/4885GNB1 3582/4885RECQL 202/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.