SCHEMBL3358989

SCHEMBL3358989

COc1cc2c(c(Cl)c1O)Oc1c(cc(OC)c(OC(=O)c3ccc4c(c3)C(=O)OC43c4cc(Cl)c(O)c(Cl)c4Oc4c3cc(Cl)c(O)c4Cl)c1Cl)C21OC(=O)c2ccc(C(=O)O)cc21

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.33
USP2 O75604 2/20 0.33
KMT2A Q03164 2/20 0.33
THRB P10828 1/20 0.33
CDK2 P24941 1/20 0.33
CHAT P28329 1/20 0.33
BLVRB P30043 1/20 0.33
RECQL P46063 1/20 0.33
BLM P54132 1/20 0.33
ACE2 Q9BYF1 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PRMT1 Q99873 1/20 0.33
GNG2 P59768 1/20 0.32
GNB1 P62873 1/20 0.32
GAA P10253 1/20 0.32
PKM P14618 1/20 0.32
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1738599 0.97 MEN1 (0.33) MEN1USP2KMT2ATHRBCDK2
SCHEMBL6037101 0.89 SMAD3 (0.32) GNG2GNB1
SCHEMBL29838713 0.86 MEN1 (0.39) MEN1USP2KMT2ATHRBCDK2
SCHEMBL16118 0.86 MEN1 (0.39) MEN1USP2KMT2ATHRBCDK2
SCHEMBL345532 0.86 GNG2 (0.40) MEN1USP2KMT2ATHRBCDK2
SCHEMBL29831001 0.86 GNG2 (0.40) MEN1USP2KMT2ATHRBCDK2
SCHEMBL29353753 0.86 MEN1 (0.39) MEN1USP2KMT2ATHRBCDK2
SCHEMBL6415591 0.83 MEN1 (0.34) MEN1USP2KMT2ATHRBCDK2
SCHEMBL6823049 0.81 RECQL (0.43) MEN1USP2KMT2ATHRBCDK2
SCHEMBL203192 0.81 GNG2 (0.43) MEN1USP2KMT2ATHRBCDK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100055803-A1 METHOD AND APPARATUS FOR DETECTING MOLECULES KOREA UNIVERSITY HOLDINGS CO., LTD. (KR) 2010-03-04 US claimed
WO-2024105137-A1 AIR-DRIED CELL MONOLAYERS AND METHODS OF PREPARING THE SAME ETH ZURICH (CH) 2024-05-23 WO disclosed
US-20240026419-A1 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITION OF CELLS ASTELLAS INSTITUTE FOR REGENERATIVE MEDICINE (US) 2024-01-25 US disclosed
EP-4306636-A2 MONOLAYER OF PBMCS OR BONE-MARROW CELLS AND USES THEREOF Exscientia GmbH (AT) 2024-01-17 EP disclosed
EP-3198276-B1 MONOLAYER OF PBMCS OR BONE-MARROW CELLS AND USES THEREOF EXSCIENTIA GMBH (AT) 2023-09-20 EP disclosed
US-20230086120-A1 MONOLAYER OF PBMCS OR BONE-MARROW CELLS AND USES THEREOF CEMM - FORSCHUNGSZENTRUM FÜR MOLEKULARE MEDIZIN GMBH (AT) 2023-03-23 US disclosed
EP-3875599-A1 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS Astellas Institute for Regenerative Medicine (US) 2021-09-08 EP disclosed
US-20210181183-A1 METHODS FOR DETERMINING SELECTIVITY OF TEST COMPOUNDS CEMM - FORSCHUNGSZENTRUM FÜR MOLEKULARE MEDIZIN GMBH (AT) 2021-06-17 US disclosed
EP-2596119-B1 METHODS FOR DETECTION OF RARE SUBPOPULATIONS OF CELLS AND HIGHLY PURIFIED COMPOSITIONS OF CELLS ASTELLAS INST FOR REGENERATIVE MEDICINE (US) 2021-04-28 EP disclosed
US-20200064348-A1 METHODS FOR DETERMINING INTERACTION BETWEEN BIOLOGICAL CELLS CEMM - FORSCHUNGSZENTRUM FÜR MOLEKULARE MEDIZIN GMBH (AT) 2020-02-27 US disclosed
US-20070054288-A1 Programmable molecular barcodes INTEL CORPORATION 2007-03-08 US disclosed
US-20070031861-A1 Methods for determining nucleotide sequence information INTEL CORPORATION 2007-02-08 US disclosed
US-20060199216-A1 Programmable molecular barcodes INTEL CORPORATION 2006-09-07 US disclosed
WO-2006066180-A1 DETECTION OF ENHANCED MULTIPLEX SIGNALS BY SURFACE ENHANCED RAMAN SPECTROSCOPY (SERS) INTEL CORPORATION (US) 2006-06-22 WO disclosed
EP-1668164-A2 PROGRAMMABLE MOLECULAR BARCODES INTEL CORPORATION (US) 2006-06-14 EP disclosed
US-20050147976-A1 Methods for determining nucleotide sequence information INTEL CORPORATION 2005-07-07 US disclosed
US-20050147977-A1 Methods and compositions for nucleic acid detection and sequence analysis INTEL CORPORATION 2005-07-07 US disclosed
US-20050147981-A1 Methods and compositions for detecting nucleic acids using scanning probe microscopy and nanocodes INTEL CORPORATION (US) 2005-07-07 US disclosed
WO-2005030996-A2 PROGRAMMABLE MOLECULAR BARCODES INTEL CORPORATION (US) 2005-04-07 WO disclosed
US-20050064435-A1 Programmable molecular barcodes INTEL CORPORATION 2005-03-24 US disclosed