Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1738366 | 0.79 | GAA (0.37) | GABRA1GABRB2GAAPOLBHPGD | |
| SCHEMBL1739369 | 0.75 | XDH (0.43) | GABRA1GABRB2GAAPOLBHPGD | |
| SCHEMBL10833768 | 0.73 | GABRA1 (0.43) | GABRA1GABRB2GAAPOLBALOX5 | |
| SCHEMBL11246327 | 0.72 | GABRA1 (0.44) | GABRA1GABRB2GAAPOLBALOX5 | |
| SCHEMBL1739395 | 0.72 | GABRA1 (0.35) | GABRA1GABRB2GAAPOLB | |
| SCHEMBL1739396 | 0.72 | GABRA1 (0.35) | GABRA1GABRB2GAAPOLB | |
| SCHEMBL10684859 | 0.71 | GABRA1 (0.52) | GABRA1GABRB2GAAPOLBHPGD | |
| SCHEMBL14928804 | 0.70 | GRIN2D (0.35) | GAA | |
| SCHEMBL3342637 | 0.70 | HPGD (0.33) | GABRA1GABRB2POLBHPGD | |
| SCHEMBL1338680 | 0.69 | HPGD (0.33) | GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2390252-A1 | New pyrazole derivatives | Almirall, S.A. (ES) | 2011-11-30 | — | — | EP | disclosed |