Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1739395 | 1.00 | GABRA1 (0.35) | GABRA1GABRB2LMNAGFERKMT2A | |
| SCHEMBL1738361 | 0.79 | LMNA (0.41) | GABRA1GABRB2LMNAGFERKMT2A | |
| SCHEMBL1738365 | 0.79 | LMNA (0.41) | GABRA1GABRB2LMNAGFERKMT2A | |
| SCHEMBL1739366 | 0.76 | ALDH1A1 (0.42) | GABRA1GABRB2LMNAGFERKMT2A | |
| SCHEMBL1739363 | 0.76 | ALDH1A1 (0.42) | GABRA1GABRB2LMNAGFERKMT2A | |
| SCHEMBL16503767 | 0.76 | SLC11A2 (0.33) | GAA | |
| SCHEMBL10833768 | 0.72 | GABRA1 (0.43) | GABRA1GABRB2KMT2AMAPTGAA | |
| SCHEMBL1739398 | 0.72 | GABRA1 (0.36) | GABRA1GABRB2GAAPOLB | |
| SCHEMBL11246327 | 0.71 | GABRA1 (0.44) | GABRA1GABRB2KMT2AMAPTGAA | |
| SCHEMBL8591081 | 0.71 | GABRA1 (0.54) | GABRA1GABRB2LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2390252-A1 | New pyrazole derivatives | Almirall, S.A. (ES) | 2011-11-30 | — | — | EP | disclosed |