SCHEMBL17396995

SCHEMBL17396995

CCCC(S(=O)(=O)c1cccc(Br)c1)S(=O)(=O)c1cccc(Br)c1

nearest known ligand 0.40

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.40
EDNRB P24530 2/20 0.40
EDNRA P25101 2/20 0.40
SMN1; SMN2 Q16637 1/20 0.38
HSD17B2 P37059 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
MMP2 P08253 2/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
PGR P06401 1/20 0.35
EGFR P00533 1/20 0.35
ERBB2 P04626 1/20 0.35
KAT6A Q92794 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
CTSL P07711 2/20 0.35
CTSS P25774 2/20 0.35
CTSK P43235 2/20 0.35
CTSC P53634 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2497291 0.84 ATM (0.41) ATMEDNRBEDNRASMN1; SMN2HSD17B2
SCHEMBL3629915 0.78 ATM (0.41) ATMEDNRBEDNRASMN1; SMN2HSD17B2
SCHEMBL1271030 0.77 HSD17B2 (0.42) ATMEDNRBEDNRAHSD17B2MMP2
SCHEMBL3415944 0.77 ATM (0.43) ATMEDNRBEDNRAHSD17B2L3MBTL1
SCHEMBL1710642 0.76 SMN1; SMN2 (0.49) ATMEDNRBEDNRASMN1; SMN2HSD17B2
SCHEMBL28813913 0.75 MMP1 (0.38) ATMEDNRBEDNRAHSD17B2L3MBTL1
SCHEMBL99072 0.74 PSIP1 (0.56) ATMEDNRBEDNRAHSD17B2MMP2
SCHEMBL3505980 0.74 ATM (0.41) ATMEDNRBEDNRAHSD17B2MMP2
SCHEMBL17397010 0.74 LARS1 (0.47) L3MBTL1MEN1KMT2A
SCHEMBL263686 0.74 ATM (0.46) ATMEDNRBEDNRAHSD17B2L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3160470-A1 ANALOGS OF PRIDOPIDINE, THEIR PREPARATION AND USE Teva Pharmaceutical Industries Ltd (IL) 2017-05-03 EP claimed
WO-2016003919-A1 ANALOGS OF PRIDOPIDINE, THEIR PREPARATION AND USE TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2016-01-07 WO claimed
EP-3160470-A1 ANALOGS OF PRIDOPIDINE, THEIR PREPARATION AND USE Teva Pharmaceutical Industries Ltd (IL) 2017-05-03 EP disclosed
WO-2016003919-A1 ANALOGS OF PRIDOPIDINE, THEIR PREPARATION AND USE TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) 2016-01-07 WO disclosed