Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.47 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 6/20 | 0.42 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.38 |
| ▸ | LSS | P48449 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.36 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28131997 | 0.75 | HTR6 (0.48) | LARS1PRMT6PRKCILRRK2KIF11 | |
| SCHEMBL30690007 | 0.75 | ALOX5 (0.53) | LARS1LRRK2KIF11 | |
| SCHEMBL17367960 | 0.75 | ALOX5 (0.53) | LARS1LRRK2KIF11 | |
| SCHEMBL17396995 | 0.74 | ATM (0.40) | L3MBTL1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL31280707 | 0.73 | ALOX5 (0.52) | LARS1LRRK2KIF11 | |
| Hydrochloric Acid SCHEMBL26666885 | 0.73 | ALOX5 (0.52) | LARS1LRRK2KIF11 | |
| SCHEMBL7430043 | 0.72 | ALDH1A1 (0.57) | LARS1LRRK2KIF11L3MBTL1MEN1 | |
| SCHEMBL17364170 | 0.71 | LARS1 (0.46) | LARS1PRMT6PRKCILRRK2KIF11 | |
| SCHEMBL4490381 | 0.68 | PRKCI (0.62) | PRMT6PRKCIKIF11CYP17A1DHFR | |
| SCHEMBL4827489 | 0.68 | LRRK2 (0.49) | LARS1PRMT6PRKCILRRK2KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160470-A1 | ANALOGS OF PRIDOPIDINE, THEIR PREPARATION AND USE | Teva Pharmaceutical Industries Ltd (IL) | 2017-05-03 | — | — | EP | disclosed |
| WO-2016003919-A1 | ANALOGS OF PRIDOPIDINE, THEIR PREPARATION AND USE | TEVA PHARMACEUTICAL INDUSTRIES LTD. (IL) | 2016-01-07 | — | — | WO | disclosed |