Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STIM1 | Q13586 | 1/20 | 0.42 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 7/20 | 0.40 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.37 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.37 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.37 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.37 |
| ▸ | GNRHR | P30968 | 5/20 | 0.37 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | FABP4 | P15090 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6476952 | 0.88 | GRIA1 (0.43) | GRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL2703670 | 0.77 | MEN1 (0.46) | GNRHRCYP3A4 | |
| SCHEMBL1740707 | 0.75 | ALDH1A1 (0.44) | STIM1ORAI1GNRHRCYP3A4FABP4 | |
| SCHEMBL23595084 | 0.74 | FABP4 (0.37) | STIM1ORAI1RORCGNRHRCYP3A4 | |
| SCHEMBL23110398 | 0.72 | HPGD (0.41) | STIM1ORAI1GNRHRCYP3A4FABP4 | |
| SCHEMBL15563837 | 0.70 | GRIA1 (0.49) | GRIA1GRIA2GRIA4GRIK5CYP3A4 | |
| SCHEMBL15564152 | 0.70 | DAO (0.57) | GRIA1GRIA2GRIA4GRIK5 | |
| SCHEMBL1642571 | 0.70 | HPGD (0.39) | STIM1ORAI1GNRHRCYP3A4FABP4 | |
| SCHEMBL12648510 | 0.70 | GNRHR (0.40) | GNRHRCYP3A4FABP4 | |
| SCHEMBL16968246 | 0.69 | DAO (0.56) | GRIA1GRIA2GRIA4GRIK5TAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2390250-B1 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS, MANUFACTURING METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | SK CHEMICALS CO LTD (KR) | 2015-08-12 | — | — | EP | disclosed |
| US-9034850-B2 | Gonadotropin releasing hormone receptor antagonist, preparation method thereof and pharmaceutical composition comprising the same | SK CHEMICALS CO., LTD. (KR) | 2015-05-19 | — | — | US | disclosed |
| US-20130137661-A1 | Gonadotropin Releasing Hormone Receptor Antagonist, Preparation Method Thereof And Pharmaceutical Composition Comprising The Same | SK CHEMICALS CO. LTD. (KR) | 2013-05-30 | — | — | US | disclosed |
| EP-2390250-A2 | GONADOTROPIN RELEASING HORMONE RECEPTOR ANTAGONISTS, MANUFACTURING METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | Sk Chemicals Co., Ltd. (KR) | 2011-11-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130137661-A1 | Gonadotropin Releasing Hormone Receptor Antagonist, Preparation Method Thereof And Pharmaceutical Composition Comprising The Same | GNRHR, GHRHR, LHCGR | STIM1 4227/4885ORAI1 1268/4885RORC 592/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.