Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.47 |
| ▸ | CPA1 | P15085 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | MMP2 | P08253 | 10/20 | 0.46 |
| ▸ | MMP3 | P08254 | 5/20 | 0.46 |
| ▸ | MMP7 | P09237 | 1/20 | 0.46 |
| ▸ | MMP1 | P03956 | 4/20 | 0.46 |
| ▸ | GNPAT | O15228 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19522131 | 0.91 | MME (0.55) | MMEALDH1A1ACECPA1ACE2 | |
| SCHEMBL29311795 | 0.85 | MMP1 (0.52) | MMEMMP2MMP3MMP7MMP1 | |
| SCHEMBL16800582 | 0.83 | MME (0.50) | MMEALDH1A1ACECPA1ACE2 | |
| SCHEMBL14567249 | 0.82 | MME (0.50) | MMELTA4HMMP2MMP3MMP1 | |
| SCHEMBL13107825 | 0.82 | SLC15A1 (0.51) | MMEALDH1A1LTA4HMMP2MMP3 | |
| SCHEMBL27267618 | 0.81 | MME (0.53) | MMEALDH1A1ACECPA1ACE2 | |
| SCHEMBL15145509 | 0.81 | MME (0.53) | MMEALDH1A1ACECPA1ACE2 | |
| SCHEMBL30999528 | 0.80 | ACE (0.59) | MMEACEMMP1GNPAT | |
| SCHEMBL17323639 | 0.79 | MMP2 (0.55) | MMEALDH1A1ACECPA1ACE2 | |
| SCHEMBL7364478 | 0.79 | GNPAT (0.48) | MMEACELTA4HMMP2MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9227996-B2 | Peptide-based quorum sensing inhibitors for the attenuation of virulence in Staphylococcus aureus | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-01-05 | — | — | US | disclosed |