SCHEMBL1740286

SCHEMBL1740286

O=C(O)Oc1c(O)ccc2[nH]nnc12

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8903374 0.79 KDM4E (0.32)
SCHEMBL6268397 0.77
SCHEMBL337778 0.75 CA12 (0.41)
SCHEMBL7478899 0.73 MAPT (0.37)
SCHEMBL8908207 0.73 ALDH1A1 (0.30)
SCHEMBL44290 0.72 LMNA (0.35)
SCHEMBL1154416 0.72
SCHEMBL378661 0.71 FGFR1 (0.30)
SCHEMBL6275824 0.71
SCHEMBL6274789 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2655527-A1 PROCESS FOR CURING SURFACE-COATING COMPOSITIONS ALLNEX AUSTRIA GmbH (AT) 2013-10-30 EP claimed
WO-2012085016-A1 PROCESS FOR CURING SURFACE-COATING COMPOSITIONS CYTEC AUSTRIA GMBH (AT) 2012-06-28 WO claimed
EP-1606447-A1 OXIDATION SYSTEM CONTAINING A MACROCYCLIC METAL COMPLEX, THE PRODUCTION THEREOF AND ITS USE Lanxess B.V. (NL) 2005-12-21 EP claimed
WO-2004083516-A1 OXIDATION SYSTEM CONTAINING A MACROCYCLIC METAL COMPLEX, THE PRODUCTION THEREOF AND ITS USE LANXESS B.V. (NL) 2004-09-30 WO claimed
EP-2255716-B1 Plasma coated sutures TYCO HEALTHCARE (US) 2012-05-09 EP disclosed
EP-2399505-A1 Plasma coates sutures Tyco Healthcare Group LP (US) 2011-12-28 EP disclosed
EP-1435829-B1 Method of improving the fray resistance of a suture. TYCO HEALTHCARE (US) 2011-07-13 EP disclosed
EP-2255716-A1 Plasma coated sutures Tyco Healthcare Group, LP (US) 2010-12-01 EP disclosed
EP-1435846-B1 PLASMA TREATED SURGICAL NEEDLES AND METHODS FOR THEIR MANUFACTURE TYCO HEALTHCARE (US) 2010-08-04 EP disclosed
EP-1435829-A4 PLASMA COATED SUTURES TYCO HEALTHCARE (US) 2009-06-17 EP disclosed
EP-1435846-A4 PLASMA TREATED SURGICAL NEEDLES AND METHODS FOR THEIR MANUFACTURE TYCO HEALTHCARE (US) 2008-06-18 EP disclosed
US-20080033485-A1 Plasma coated sutures TYCO HEALTHCARE GROUP LP 2008-02-07 US disclosed
EP-1251973-A4 PLASMA-DEPOSITED COATINGS, DEVICES AND METHODS BIOSURFACE ENG TECH INC (US) 2003-07-23 EP disclosed
WO-2003037156-A2 PLASMA COATED SUTURES TYCO HEALTHCARE GROUP L.P. (US) 2003-05-08 WO disclosed
US-6558409-B1 Plasma treated surgical needles and methods for their manufacture TYCO HEALTHCARE GROUP LP 2003-05-06 US disclosed
US-20030074022-A1 PLASMA TREATED SURGICAL NEEDLES AND METHODS FOR THEIR MANUFACTURE COVIDIEN LP 2003-04-17 US disclosed
WO-2003028770-A2 PLASMA TREATED SURGICAL NEEDLES AND METHODS FOR THEIR MANUFACTURE TYCO HEATHCARE GROUP, LP (US) 2003-04-10 WO disclosed
EP-1251973-A1 PLASMA-DEPOSITED COATINGS, DEVICES AND METHODS Biosurface Engineering Technologies, Inc. (US) 2002-10-30 EP disclosed
US-20020009604-A1 Plasma treatment of an implantable medical device surface with of nitrogen and/or oxygen molecules, e.g., ammonia, nitrogen oxide, oxygen etc.; anticoagulants, -inflammatory agents; less restenoisis, fibrosis BIOSURFACE ENGINEERING TECHNOLOGIES, INC. 2002-01-24 US disclosed
WO-2001045862-A1 PLASMA-DEPOSITED COATINGS, DEVICES AND METHODS BIOSURFACE ENGINEERING TECHNOLOGIES, INC. (US) 2001-06-28 WO disclosed