Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.53 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.53 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | NOX1 | Q9Y5S8 | 2/20 | 0.50 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11888837 | 0.88 | RXRA (0.56) | SMN1; SMN2NPC1RAB9AMAOBLMNA | |
| SCHEMBL28018068 | 0.86 | FFAR1 (0.56) | MAOBPARP10FFAR1FFAR4 | |
| SCHEMBL20477163 | 0.79 | RAB9A (0.46) | KDM4ESMN1; SMN2NPC1RAB9AS1PR5 | |
| SCHEMBL28010585 | 0.78 | KDM1A (0.56) | SMN1; SMN2NPC1RAB9AMAOBCHRM2 | |
| SCHEMBL14975421 | 0.77 | ALOX5 (0.48) | NR4A1NR4A2NR4A3ALOX5PTGS1 | |
| SCHEMBL8935257 | 0.75 | ALOX5 (0.52) | KDM4EKMT2ASMN1; SMN2NR4A1NR4A2 | |
| SCHEMBL2362048 | 0.75 | NPC1 (0.45) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL28017518 | 0.74 | CHRM2 (0.50) | KDM4EKMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL8935254 | 0.74 | ALOX5 (0.54) | KDM4EKMT2ASMN1; SMN2NR4A1NR4A2 | |
| SCHEMBL5702266 | 0.74 | L3MBTL1 (0.63) | NR4A1NR4A2NR4A3ALOX5PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102947265-B | Methionin specific demethylase-1 inhibitor and application thereof | ORYZON GENOMICS, S.A. (ES) | 2015-07-29 | — | — | CN | disclosed |
| EP-2389362-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | Oryzon Genomics, S.A. (ES) | 2011-11-30 | — | — | EP | disclosed |
| US-20110252680-A1 | Surface mounted frame arrangement | ROSE DISPLAYS, LTD | 2011-10-20 | — | — | US | disclosed |
| WO-2010084160-A1 | PHENYLCYCLOPROPYLAMINE DERIVATIVES AND THEIR MEDICAL USE | ORYZON GENOMICS S.A. (ES) | 2010-07-29 | — | — | WO | disclosed |