SCHEMBL174072

SCHEMBL174072

C=CC(=O)Nc1cccc(NC(=O)C=C)n1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TGM2 P21980 2/20 0.53
BTK Q06187 2/20 0.52
ITK Q08881 2/20 0.52
TEK Q02763 7/20 0.51
EPHB4 P54760 6/20 0.51
KDR P35968 4/20 0.51
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
KDM4E B2RXH2 2/20 0.50
NPC1 O15118 2/20 0.50
LMNA P02545 2/20 0.50
MAPT P10636 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
POLB P06746 1/20 0.50
BLM P54132 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
HPGD P15428 1/20 0.50
PSMD14 O00487 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9952792 0.87 CHRNB2 (0.52) TGM2BTKITKTEKEPHB4
SCHEMBL31357334 0.87 CHRNB2 (0.52) TGM2BTKITKTEKEPHB4
SCHEMBL2119085 0.87 XIAP (0.55) TGM2BTKITKTEKEPHB4
SCHEMBL28443489 0.86 KDM4E (0.63) TGM2BTKITKTEKEPHB4
SCHEMBL30469520 0.86 KDM4E (0.63) TGM2BTKITKTEKEPHB4
SCHEMBL28449040 0.82 ALDH1A1 (0.49) TGM2BTKITKTEKEPHB4
SCHEMBL31415848 0.82 KDM4E (0.44) TGM2BTKITKTEKEPHB4
SCHEMBL1147615 0.79 NPC1 (0.63) TGM2MEN1KMT2AKDM4ENPC1
SCHEMBL31415846 0.78 MAPT (0.46) TEKEPHB4KDRMEN1KMT2A
SCHEMBL32681801 0.78 NPC1 (0.59) TGM2KMT2ANPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118829398-A System and method for a personal wearable electronic device 麻省理工学院 2024-10-22 CN claimed
US-20240181430-A1 POROUS SORPTIVE SOLID PHASE MICROEXTRACTION DEVICES AND PREPARATION THEREOF MEMORIAL UNIVERSITY OF NEWFOUNDLAND (CA) 2024-06-06 US claimed
EP-4294559-A1 POROUS SORPTIVE SOLID PHASE MICROEXTRACTION DEVICES AND PREPARATION THEREOF Memorial University of Newfoundland (CA) 2023-12-27 EP claimed
US-20230277159-A1 SYSTEMS AND METHODS FOR ON-PERSON WEARABLE ELECTRONIC DEVICES MASSACHUSETTS INSTITUTE OF TECHNOLOGY 2023-09-07 US claimed
WO-2023168111-A1 SYSTEMS AND METHODS FOR ON-PERSON WEARABLE ELECTRONIC DEVICES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2023-09-07 WO claimed
EP-3846691-A2 SYSTEM FOR DETECTION OF VOLATILE ORGANIC COMPOUNDS (VOC) IN EXHALED BREATH FOR HEALTH MONITORING Kozhnosys Private Limited (IN) 2021-07-14 EP claimed
WO-2021020630-A1 ZINC ION-IMPRINTED POLYMER AND PREPARATION METHOD THEREFOR 서울여자대학교 산학협력단 2021-02-04 WO claimed
US-10772822-B2 Molecularly imprinted polymers and their use as antidandruff agents L'OREAL (FR) 2020-09-15 US claimed
CN-109174036-A A kind of high molecular polymer adsorbent and the preparation method and application thereof 浙江工业大学 2019-01-11 CN claimed
WO-2016189141-A1 METHOD FOR THE DETERMINATION OF TARGETS OF BIOTINYLATED MOLECULES UNIVERSITAT AUTONOMA DE BARCELONA (ES) 2016-12-01 WO claimed
US-20150320667-A1 MOLECULARLY IMPRINTED POLYMER FOR SELECTIVELY TRAPPING ODOROUS MOLECULES L'OREAL (FR) 2015-11-12 US claimed
WO-2012028825-A1 ULTRA-THIN FILMS OF MOLECULARLY IMPRINTED POLYMERS CONFINED TO THE SURFACE OF A SUBSTRATE UNIVERSITE PARIS DIDEROT-PARIS 7 (FR) 2012-03-08 WO claimed
CN-101712669-B Method for separating and purifying luteolin UNIV HEBEI POLYTECHNIC 2012-01-18 CN claimed
US-7750090-B2 Moleculary imprinted polymers for extraction of components from foodstruffs MIP TECHNOLOGIES AB (SE) 2010-07-06 US claimed
CN-101712669-A Method for separating and purifying luteolin UNIV HEBEI POLYTECHNIC 2010-05-26 CN claimed
WO-2010025853-A1 MOLECULARLY IMPRINTED POLYMER (MIP) CHIP SENSOR, USE THEREOF, AND ANALYTICAL DETECTION METHOD KIST-EUROPE FORSCHUNGSGESELLSCHAFT MBH (DE) 2010-03-11 WO claimed
CN-100497676-C Solid phase extraction process for extracting and separating palladium UNIV YUNNAN (CN) 2009-06-10 CN claimed
CN-101177500-A Method for preparing bisphenol A molecular engram polymer HUBEI IMP AND EXP INSPECTION A (CN) 2008-05-14 CN claimed
CN-101020964-A Solid phase extraction process for extracting and separating palladium UNIV YUNNAN (CN) 2007-08-22 CN claimed
US-6177513-B1 Method for evaluating artificial receptors TOSHIFUMI TAKEUCHI (JP) 2001-01-23 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10772822-B2 Molecularly imprinted polymers and their use as antidandruff agents DNMT1, POLR1C, ETF1 TGM2 3785/4885BTK 4739/4885ITK 4096/4885
US-20150320667-A1 MOLECULARLY IMPRINTED POLYMER FOR SELECTIVELY TRAPPING ODOROUS MOLECULES OR10J3, OR51E2, MSMO1 TGM2 4642/4885BTK 1600/4885ITK 2981/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.