SCHEMBL30469520

SCHEMBL30469520

C=CC(=O)Nc1cccc(C(=O)O)n1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.63
LMNA P02545 1/20 0.63
ALOX15 P16050 1/20 0.52
TSHR P16473 1/20 0.52
ACMSD Q8TDX5 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
TGM2 P21980 1/20 0.49
EGFR P00533 1/20 0.47
BTK Q06187 2/20 0.46
ITK Q08881 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TEK Q02763 7/20 0.45
EPHB4 P54760 6/20 0.45
KDR P35968 4/20 0.45
GRM5 P41594 1/20 0.45
GSTO1 P78417 3/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28443489 1.00 KDM4E (0.63) KDM4ELMNAALOX15TSHRACMSD
SCHEMBL174072 0.86 TGM2 (0.53) KDM4ELMNATDP1TGM2EGFR
SCHEMBL28449040 0.83 ALDH1A1 (0.49) KDM4ELMNATGM2BTKITK
SCHEMBL9952792 0.78 CHRNB2 (0.52) LMNATGM2EGFRBTKITK
SCHEMBL31357334 0.78 CHRNB2 (0.52) LMNATGM2EGFRBTKITK
SCHEMBL2119085 0.78 XIAP (0.55) KDM4ETGM2EGFRBTKITK
SCHEMBL2251120 0.77 KDM4E (1.00) KDM4ELMNAALOX15TSHRACMSD
SCHEMBL29484609 0.77 KDM4E (1.00) KDM4ELMNAALOX15TSHRACMSD
SCHEMBL28937146 0.76 KMT2A (0.79) KDM4ELMNAALOX15TSHRACMSD
SCHEMBL14413884 0.73 KDM4E (0.68) KDM4ELMNAALOX15TSHRACMSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116285191-B Preparation method of high-strength, high-toughness, self-repairing and multicolor fluorescence temperature-sensitive hydrogel 山东师范大学 2024-11-22 CN claimed
CN-116285191-A Preparation method of high-strength, high-toughness, self-repairing and multicolor fluorescence temperature-sensitive hydrogel 山东师范大学 2023-06-23 CN claimed