SCHEMBL17412430

SCHEMBL17412430

Clc1cc(-c2cc3ccccc3c3ccccc23)nc(-c2cc3ccccc3c3ccccc23)n1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSP90AA1 P07900 4/20 0.41
HSP90AB1 P08238 4/20 0.41
CYP11B1 P15538 1/20 0.41
NISCH Q9Y2I1 1/20 0.39
KMT2A Q03164 1/20 0.39
ALDH1A1 P00352 3/20 0.39
HSD17B10 Q99714 3/20 0.39
HIF1A Q16665 2/20 0.39
L3MBTL1 Q9Y468 2/20 0.39
MAPK1 P28482 2/20 0.39
TSHR P16473 2/20 0.39
HPGD P15428 1/20 0.39
CASP1 P29466 1/20 0.39
TRPM4 Q8TD43 1/20 0.38
CYP1B1 Q16678 1/20 0.38
LMNA P02545 2/20 0.36
KDM4E B2RXH2 1/20 0.36
CYP3A4 P08684 1/20 0.36
MAPT P10636 1/20 0.36
APEX1 P27695 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28541027 0.91 CYP11B1 (0.44) CYP11B1NISCHKMT2AALDH1A1HSD17B10
SCHEMBL17412410 0.88 LMNA (0.51) HSP90AA1HSP90AB1CYP11B1KMT2AALDH1A1
SCHEMBL17412390 0.88 KDM4E (0.51) HSP90AA1HSP90AB1CYP11B1KMT2AALDH1A1
SCHEMBL24030394 0.86 ALDH1A1 (0.41) HSP90AA1HSP90AB1CYP11B1NISCHKMT2A
SCHEMBL17412415 0.85 LMNA (0.49) HSP90AA1HSP90AB1CYP11B1KMT2AALDH1A1
SCHEMBL22274009 0.81 LMNA (0.47) HSP90AA1HSP90AB1CYP11B1KMT2AALDH1A1
SCHEMBL22274007 0.81 KDM4E (0.47) HSP90AA1HSP90AB1CYP11B1KMT2AALDH1A1
SCHEMBL13314087 0.80 CYP11B1 (0.52) CYP11B1NISCHKMT2AALDH1A1HSD17B10
SCHEMBL17412418 0.80 CYP1A2 (0.42) HSP90AA1HSP90AB1KMT2AALDH1A1HSD17B10
SCHEMBL28765274 0.80 ACACA (0.52) KMT2AALDH1A1HPGDLMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016003225-A2 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2016-01-07 WO disclosed