Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 20/20 | 0.49 |
| ▸ | JAK2 | O60674 | 6/20 | 0.48 |
| ▸ | JAK1 | P23458 | 6/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17413192 | 0.92 | BTK (0.42) | JAK3JAK2JAK1 | |
| SCHEMBL17412969 | 0.84 | BTK (0.59) | JAK3JAK2JAK1 | |
| SCHEMBL17413194 | 0.83 | JAK3 (0.43) | JAK3JAK2JAK1 | |
| SCHEMBL17413148 | 0.83 | JAK3 (0.58) | JAK3JAK2JAK1 | |
| SCHEMBL17412970 | 0.81 | JAK3 (0.70) | JAK3JAK2JAK1 | |
| SCHEMBL17412959 | 0.77 | SYK (0.57) | JAK3JAK2JAK1 | |
| SCHEMBL17413040 | 0.77 | JAK3 (0.58) | JAK3JAK2JAK1 | |
| SCHEMBL17413159 | 0.76 | JAK3 (0.50) | JAK3JAK2JAK1 | |
| SCHEMBL17412995 | 0.76 | BTK (0.54) | JAK3 | |
| SCHEMBL17412962 | 0.75 | JAK3 (0.70) | JAK3JAK2JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016000615-A1 | HETEROARYL COMPOUNDS AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-01-07 | — | — | WO | disclosed |