Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | PYCR1 | P32322 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | PARP1 | P09874 | 2/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15886177 | 0.81 | IDO1 (0.34) | — | |
| SCHEMBL15875002 | 0.76 | CHRM2 (0.37) | ALDH1A1TSHRCYP2D6MEN1KMT2A | |
| SCHEMBL4678470 | 0.69 | CYP2C19 (0.52) | NOS1ALDH1A1TSHRHPGDHTR7 | |
| SCHEMBL18883812 | 0.68 | GABRA1 (0.38) | ALDH1A1TSHR | |
| SCHEMBL4243270 | 0.68 | HTR2A (0.56) | ALDH1A1TSHRCYP3A4CYP2D6LMNA | |
| Hydrochloric Acid SCHEMBL8390076 | 0.66 | IDO1 (0.54) | ALDH1A1TSHRCYP3A4CYP2D6LMNA | |
| SCHEMBL989636 | 0.66 | ALDH1A1 (0.67) | NOS1ALDH1A1TSHRHPGDHTR7 | |
| SCHEMBL16398676 | 0.65 | ALDH1A1 (0.45) | NOS1ALDH1A1TSHRPYCR1HPGD | |
| SCHEMBL31721197 | 0.65 | TSHR (0.48) | NOS1ALDH1A1TSHRPYCR1HPGD | |
| SCHEMBL12857 | 0.63 | ALDH1A1 (0.56) | NOS1ALDH1A1TSHRHPGDCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170145152-A1 | GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN METATHESIS REACTION | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2017-05-25 | — | — | US | disclosed |
| US-20170145152-A1 | GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN METATHESIS REACTION | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2017-05-25 | — | — | US | disclosed |
| WO-2016000242-A1 | GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN METATHESIS REACTION | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2016-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170145152-A1 | GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN METATHESIS REACTION | F8, COASY, FADS1 | NOS1 3217/4885ALDH1A1 1858/4885TSHR 4178/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.