Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18883812 | 0.83 | GABRA1 (0.38) | CHRM3ALDH1A1GABRA1GABRB2TRPA1 | |
| SCHEMBL11082289 | 0.83 | ALDH1A1 (0.38) | ALDH1A1KIF11KDM4EPABPC1APOBEC3A | |
| SCHEMBL362964 | 0.80 | TSHR (0.43) | ALDH1A1KDM4EPABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL15171994 | 0.78 | ESR1 (0.37) | ALDH1A1KDM4EPABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL4796677 | 0.77 | MEN1 (0.44) | ALDH1A1KIF11ESR1ESR2MEN1 | |
| SCHEMBL8129683 | 0.76 | KIF11 (0.41) | CHRM2CHRM3ALDH1A1KIF11MEN1 | |
| Dimethylamine SCHEMBL8511811 | 0.76 | KCNN4 (0.43) | ALDH1A1KDM4EPABPC1APOBEC3AAPOBEC3G | |
| SCHEMBL15886168 | 0.76 | ALDH1A1 (0.36) | CHRM2CHRM1CHRM3ALDH1A1KDM4E | |
| SCHEMBL17352348 | 0.76 | ALDH1A1 (0.36) | CHRM2CHRM1CHRM3ALDH1A1KDM4E | |
| SCHEMBL17413632 | 0.76 | NOS1 (0.38) | ALDH1A1MEN1KMT2ATSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10159966-B2 | Catalyst complexes with carbene ligand and method for making same and use in metathesis reaction | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2018-12-25 | — | — | US | disclosed |
| WO-2016000242-A1 | GROUP 8 TRANSITION METAL CATALYSTS AND METHOD FOR MAKING SAME AND PROCESS FOR USE OF SAME IN METATHESIS REACTION | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2016-01-07 | — | — | WO | disclosed |
| US-20150367338-A1 | CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2015-12-24 | — | — | US | disclosed |
| US-20150367338-A1 | CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2015-12-24 | — | — | US | disclosed |
| US-20150367338-A1 | CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2015-12-24 | — | — | US | disclosed |
| EP-2943499-A1 | CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION | Guangming Innovation Company (Wuhan) (CN) | 2015-11-18 | — | — | EP | disclosed |
| WO-2014108071-A1 | CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2014-07-17 | — | — | WO | disclosed |
| WO-2014108071-A1 | CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION | GUANG MING INNOVATION COMPANY (WUHAN) (CN) | 2014-07-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10159966-B2 | Catalyst complexes with carbene ligand and method for making same and use in metathesis reaction | MSMO1, ALOX12, SQLE | CHRM2 434/4885CHRM1 120/4885CHRM3 611/4885 |
| US-20150367338-A1 | CATALYST COMPLEXES WITH CARBENE LIGAND AND METHOD FOR MAKING SAME AND USE IN METATHESIS REACTION | MSMO1, ALOX12, SQLE | CHRM2 434/4885CHRM1 120/4885CHRM3 611/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.