Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
| ▸ | NR3C2 | P08235 | 4/20 | 0.32 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.31 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17414238 | 0.86 | IDO1 (0.42) | IDO1NR3C2NR3C1P2RX7CA3 | |
| SCHEMBL5823911 | 0.82 | CYP3A4 (0.34) | IDO1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL21403423 | 0.82 | IDO1 (0.46) | IDO1KIF11P2RX7SLC6A2SLC6A4 | |
| SCHEMBL29875850 | 0.82 | IDO1 (0.46) | IDO1KIF11P2RX7SLC6A2SLC6A4 | |
| SCHEMBL13547861 | 0.80 | PTGS1 (0.40) | IDO1NR3C2NR3C1SLC6A2SLC6A4 | |
| SCHEMBL2625769 | 0.73 | IDO1 (0.42) | IDO1NR3C2NR3C1SLC6A2SLC6A4 | |
| SCHEMBL3309883 | 0.73 | IDO1 (0.40) | IDO1CA3CA6CA5ACA9 | |
| SCHEMBL31085527 | 0.73 | IDO1 (0.40) | IDO1CA3CA6CA5ACA9 | |
| SCHEMBL17696933 | 0.72 | CA3 (0.50) | IDO1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL31529917 | 0.72 | IDO1 (0.36) | IDO1KIF11CA3CA6CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9856732-B2 | Tracers | RESTRACK AS (NO) | 2018-01-02 | — | — | US | disclosed |
| EP-2935508-B1 | TRACERS | RESTRACK AS (NO) | 2017-02-15 | — | — | EP | disclosed |
| US-20160003040-A1 | Tracers | Resman Technology AS (NO) | 2016-01-07 | — | — | US | disclosed |
| US-20160003040-A1 | Tracers | Resman Technology AS (NO) | 2016-01-07 | — | — | US | disclosed |