SCHEMBL17696933

SCHEMBL17696933

Oc1cc(F)ccc1C(Cl)(Cl)Cl

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA3 P07451 1/20 0.50
CA6 P23280 1/20 0.50
CA5A P35218 1/20 0.50
CA9 Q16790 1/20 0.50
CA14 Q9ULX7 1/20 0.50
CA5B Q9Y2D0 1/20 0.50
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
PTGS1 P23219 1/20 0.35
PTGS2 P35354 1/20 0.35
NR3C1 P04150 2/20 0.33
PGR P06401 2/20 0.33
NR3C2 P08235 2/20 0.33
MAOB P27338 1/20 0.33
KCNN4 O15554 1/20 0.33
DAO P14920 2/20 0.32
KDM4E B2RXH2 2/20 0.32
IDO1 P14902 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17696928 0.82 CA3 (0.44) CA3CA6CA5ACA9CA14
SCHEMBL29427775 0.79 CA3 (0.52) CA3CA6CA5ACA9CA14
SCHEMBL4343525 0.79 CA3 (0.52) CA3CA6CA5ACA9CA14
SCHEMBL12731992 0.77 ALDH1A1 (0.54) CA3CA6CA5ACA9CA14
SCHEMBL11550172 0.76 ALDH1A1 (0.42) CA3CA6CA5ACA9CA14
SCHEMBL31433155 0.76 ALDH1A1 (0.42) CA3CA6CA5ACA9CA14
SCHEMBL31297347 0.74 TSHR (0.60) CA3CA6CA5ACA9CA14
SCHEMBL3978795 0.74 TSHR (0.60) CA3CA6CA5ACA9CA14
SCHEMBL17414239 0.72 IDO1 (0.33) CA3CA6CA5ACA9CA14
SCHEMBL30965844 0.71 CA3 (0.42) CA3CA6CA5ACA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2016059242-A2 TRACERS INSTITUTT FOR ENERGITEKNIKK (NO) 2016-04-21 WO disclosed