Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LEF1 | Q9UJU2 | 1/20 | 0.48 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.42 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.42 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | F7 | P08709 | 1/20 | 0.41 |
| ▸ | F3 | P13726 | 1/20 | 0.41 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22238249 | 0.89 | LEF1 (0.47) | LEF1MMP13AURKBEGFRRAF1 | |
| SCHEMBL17414823 | 0.87 | MMP13 (0.64) | LEF1MMP13KDM4EALDH1A1HPGD | |
| SCHEMBL3030225 | 0.87 | LEF1 (0.60) | LEF1PIN1MMP13SMAD3KDM4E | |
| SCHEMBL29830077 | 0.83 | LEF1 (0.67) | LEF1PIN1MMP13KDM4EALDH1A1 | |
| SCHEMBL19885734 | 0.80 | LEF1 (0.61) | LEF1PIN1EGFRKDM4ELMNA | |
| SCHEMBL8196470 | 0.79 | SMAD3 (0.57) | PIN1MMP13SMAD3KDM4EALDH1A1 | |
| SCHEMBL6512022 | 0.78 | MMP13 (0.55) | PIN1MMP13SMAD3KDM4EALDH1A1 | |
| SCHEMBL8693590 | 0.78 | CA1 (0.54) | AURKBEGFRRAF1KDRMAP2K2 | |
| SCHEMBL3035898 | 0.77 | LEF1 (0.49) | LEF1PIN1SMAD3KDM4EHPGD | |
| SCHEMBL28291195 | 0.77 | CA12 (0.45) | LEF1PIN1MMP13F11HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210106689-A1 | Saccharide Derivative of a Toxic Payload and Antibody Conjugates Thereof | GLYKOS FINLAND OY (FI) | 2021-04-15 | — | — | US | disclosed |
| US-10973920-B2 | Saccharide derivative of a toxic payload and antibody conjugates thereof | GLYKOS FINLAND OY (FI) | 2021-04-13 | — | — | US | disclosed |
| EP-3160513-B1 | SACCHARIDE DERIVATIVE OF A TOXIC PAYLOAD AND ANTIBODY CONJUGATES THEREOF | GLYKOS FINLAND OY (FI) | 2020-02-12 | — | — | EP | disclosed |
| WO-2016001485-A1 | SACCHARIDE DERIVATIVE OF A TOXIC PAYLOAD AND ANTIBODY CONJUGATES THEREOF | GLYKOS FINLAND OY (FI) | 2016-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210106689-A1 | Saccharide Derivative of a Toxic Payload and Antibody Conjugates Thereof | FUT5, STT3A, CD44 | LEF1 4460/4885PIN1 2436/4885MMP13 1017/4885 |
| US-10973920-B2 | Saccharide derivative of a toxic payload and antibody conjugates thereof | FUT5, STT3A, CD44 | LEF1 4460/4885PIN1 2436/4885MMP13 1017/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.