SCHEMBL17415076

SCHEMBL17415076

CC(C)(C)c1ccc(-c2cccc3c2C=CC3[Hf](C)(C)(C)(=[SiH2])(C2CCCCC2)C2C=Cc3c(-c4ccc(C(C)(C)C)cc4)cccc32)cc1

nearest known ligand 0.31

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
BRD4 O60885 1/20 0.31
CREBBP Q92793 1/20 0.31
EPHX1 P07099 1/20 0.30
EPHX2 P34913 1/20 0.30
PTGS2 P35354 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17414910 0.91 BRD4 (0.32) BRD4CREBBP
SCHEMBL17415594 0.90
SCHEMBL17415317 0.89 PTPN5 (0.34)
SCHEMBL17415045 0.87 PTGS2 (0.32) PTGS2
SCHEMBL17416153 0.87 PTGS2 (0.33) PTGS2
SCHEMBL17415426 0.86 ALDH1A1 (0.32)
SCHEMBL17415337 0.85 BRD4 (0.31) BRD4CREBBPEPHX1EPHX2PTGS2
SCHEMBL17415824 0.84 PTGS2 (0.30) PTGS2
SCHEMBL17415890 0.84 PTGS2 (0.32) PTGS2
SCHEMBL17415544 0.83 BRD4 (0.33) BRD4CREBBP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2966096-B1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP (JP) 2017-04-26 EP disclosed
EP-2966096-A1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER Japan Polyethylene Corporation (JP) 2016-01-13 EP disclosed