SCHEMBL17416153

SCHEMBL17416153

C[Hf](C)(C)(=[SiH2])(C1CCCCC1)(C1C=Cc2c(-c3ccccc3)cccc21)C1C=Cc2c(-c3ccccc3)cccc21

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
HTR1A P08908 4/20 0.30
HTR7 P34969 4/20 0.30
CYP11B2 P19099 1/20 0.30
BCHE P06276 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17415890 0.96 PTGS2 (0.32) PTGS2MEN1KMT2AALDH1A1LMNA
SCHEMBL17415045 0.90 PTGS2 (0.32) PTGS2
SCHEMBL17415911 0.90 HTR1A (0.32) PTGS2HTR1AHTR7CYP11B2
SCHEMBL17415414 0.88 CASP3 (0.33) MEN1KMT2AALDH1A1LMNASMN1; SMN2
SCHEMBL17415337 0.88 BRD4 (0.31) PTGS2SMN1; SMN2
SCHEMBL17415076 0.87 BRD4 (0.31) PTGS2
SCHEMBL17415824 0.87 PTGS2 (0.30) PTGS2
SCHEMBL17415226 0.87
SCHEMBL17415576 0.86
SCHEMBL17415143 0.86 HTR1A (0.31) PTGS2HTR1AHTR7CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2966096-B1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP (JP) 2017-04-26 EP disclosed
EP-2966096-A1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER Japan Polyethylene Corporation (JP) 2016-01-13 EP disclosed