Sugi Predict

Sugi Predict / Compounds / SCHEMBL17415469

SCHEMBL17415469

SCHEMBL17415469

CC(C)c1cccc(-c2cccc3c2C=CC3[Hf](C)(C)(=[SiH2])(C2C=Cc3c(-c4cccc(C(C)C)c4)cccc32)(C(C)(C)C)C(C)(C)C)c1

nearest known ligand 0.34

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ BRD4 O60885 1/20 0.33
▸ CREBBP Q92793 1/20 0.33
▸ RXRA P19793 2/20 0.32
▸ RXRB P28702 1/20 0.32
▸ RXRG P48443 1/20 0.32
▸ PTPN5 P54829 3/20 0.31
▸ NR4A2 P43354 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17415666 0.90 BRD4 (0.31) BRD4CREBBP
SCHEMBL17415212 0.89 BRD4 (0.35) BRD4CREBBPRXRARXRBRXRG
SCHEMBL17415031 0.87 RXRA (0.35) BRD4CREBBPRXRARXRBRXRG
SCHEMBL17415278 0.85 BRD4 (0.33) BRD4CREBBPRXRARXRBRXRG
SCHEMBL17415504 0.85 BRD4 (0.33) BRD4CREBBPRXRARXRBRXRG
SCHEMBL17415181 0.84 CA12 (0.33) —
SCHEMBL17415447 0.84 RXRA (0.33) BRD4CREBBPRXRARXRBRXRG
SCHEMBL17415726 0.84 RXRA (0.33) BRD4CREBBPRXRARXRBRXRG
SCHEMBL17416060 0.83 HTR1A (0.31) —
SCHEMBL17414967 0.83 KIF11 (0.35) RXRARXRBPTPN5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2966096-B1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER JAPAN POLYETHYLENE CORP (JP) 2017-04-26 — — EP disclosed
EP-2966096-A1 METHOD FOR PRODUCING ETHYLENE/ -OLEFIN COPOLYMER Japan Polyethylene Corporation (JP) 2016-01-13 — — EP disclosed