SCHEMBL17417249

SCHEMBL17417249

CO[Si](OC)(OC)C(Cc1ccccc1)NCCN

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.39
SIGMAR1 Q99720 13/20 0.39
SLC6A2 P23975 3/20 0.38
TAAR1 Q96RJ0 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
MAOA P21397 1/20 0.38
CYP2A6 P11509 1/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
ADRB2 P07550 1/20 0.36
ADRB1 P08588 1/20 0.36
HTR1A P08908 1/20 0.36
ADORA3 P0DMS8 1/20 0.36
DRD2 P14416 1/20 0.36
ADRA2B P18089 1/20 0.36
ADRA2C P18825 1/20 0.36
CNR1 P21554 1/20 0.36
HTR2A P28223 1/20 0.36
MC4R P32245 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL37759 0.76 ALDH1A1 (0.38) ALDH1A1SIGMAR1SLC6A2TAAR1SLC6A4
SCHEMBL20357548 0.76 SIGMAR1 (0.42) ALDH1A1SIGMAR1SLC6A2TAAR1SLC6A4
SCHEMBL447452 0.75 ALDH1A1 (0.40) ALDH1A1SIGMAR1SLC6A2TAAR1SLC6A4
SCHEMBL5577576 0.73 SIGMAR1 (0.70) SIGMAR1SLC6A2TAAR1SLC6A4SLC6A3
SCHEMBL614445 0.72 ALDH1A1 (0.49) ALDH1A1SIGMAR1SLC6A2TAAR1SLC6A4
SCHEMBL9638325 0.72 SIGMAR1 (0.47) SIGMAR1SLC6A2TAAR1SLC6A4SLC6A3
SCHEMBL2145475 0.72
SCHEMBL361861 0.72
SCHEMBL20210786 0.72
SCHEMBL6936702 0.71 ALDH1A1 (0.58) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9879362-B2 Method for producing nanofibers capable of storing and transferring nitric oxide and nanofibers capable of storing and transferring nitric oxide produced thereby I-SENS, INC. (KR) 2018-01-30 US claimed
US-20160010241-A1 METHOD FOR PRODUCING NANOFIBERS CAPABLE OF STORING AND TRANSFERRING NITRIC OXIDE AND NANOFIBERS CAPABLE OF STORING AND TRANSFERRING NITRIC OXIDE PRODUCED THEREBY I-SENS, INC. (KR) 2016-01-14 US claimed
US-9879362-B2 Method for producing nanofibers capable of storing and transferring nitric oxide and nanofibers capable of storing and transferring nitric oxide produced thereby I-SENS, INC. (KR) 2018-01-30 US disclosed
US-20160010241-A1 METHOD FOR PRODUCING NANOFIBERS CAPABLE OF STORING AND TRANSFERRING NITRIC OXIDE AND NANOFIBERS CAPABLE OF STORING AND TRANSFERRING NITRIC OXIDE PRODUCED THEREBY I-SENS, INC. (KR) 2016-01-14 US disclosed