⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1518987 | 0.85 | ADAM17 (0.32) | — | |
| SCHEMBL1408376 | 0.74 | MAPT (0.35) | — | |
| SCHEMBL5881899 | 0.72 | APEX1 (0.33) | — | |
| SCHEMBL7851784 | 0.72 | POLB (0.34) | — | |
| SCHEMBL5061804 | 0.72 | BRD4 (0.33) | — | |
| SCHEMBL2239318 | 0.72 | — | — | |
| SCHEMBL10344448 | 0.69 | MAPK1 (0.39) | — | |
| SCHEMBL31235575 | 0.69 | MT-CO2 (0.33) | — | |
| SCHEMBL8569950 | 0.69 | DPP4 (0.35) | — | |
| SCHEMBL8569954 | 0.69 | DPP4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2388589-B1 | Plasma membrane isolation | IMEC (BE) | 2015-09-30 | — | — | EP | disclosed |
| US-20150197742-A1 | Plasma Membrane Isolation | KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) | 2015-07-16 | — | — | US | disclosed |
| US-8936935-B2 | Plasma membrane isolation | IMEC (BE) | 2015-01-20 | — | — | US | disclosed |
| EP-2388589-A1 | Plasma membrane isolation | IMEC (BE) | 2011-11-23 | — | — | EP | disclosed |
| US-8037975-B2 | Piston seal member and disc brake using the piston seal member | NISSIN KOGYO CO., LTD. (JP) | 2011-10-18 | — | — | US | disclosed |
| US-20050196823-A1 | Methods and apparatus for gel-free qualitative and quantitative proteome analysis, and uses therefore | PRONOTA NV (BE) | 2005-09-08 | — | — | US | disclosed |
| US-6908740-B2 | Methods and apparatus for gel-free qualitative and quantitative proteome analysis, and uses therefore | MYCARTIS NV (BE) | 2005-06-21 | — | — | US | disclosed |
| EP-1370571-B1 | METHODS AND APPARATUS FOR GEL-FREE QUALITATIVE AND QUANTITATIVE PROTEOME ANALYSIS, AND USES THEREFOR | VLAAMS INTERUNIV INST BIOTECH (BE) | 2005-06-15 | — | — | EP | disclosed |
| US-20040005633-A1 | Methods and apparatuses for gel-free qualitative and quantitative proteome analysis, and uses therefore | MYCARTIS NV (BE) | 2004-01-08 | — | — | US | disclosed |
| EP-1370571-A2 | METHODS AND APPARATUS FOR GEL-FREE QUALITATIVE AND QUANTITATIVE PROTEOME ANALYSIS, AND USES THEREFOR | Vlaams Interuniversitair Instituut voor Biotechnologie vzw. (BE) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002077016-A2 | METHODS AND APPARATUS FOR GEL-FREE QUALITATIVE AND QUANTITATIVE PROTEOME ANALYSIS, AND USES THEREFORE | VLAAMS INTERUNIVERSITAIR INSTITUUT VOOR BIOTECHNOLOGIE VZW (BE) | 2002-10-03 | — | — | WO | disclosed |