Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
| ▸ | AADAT | Q8N5Z0 | 8/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | GOT1 | P17174 | 1/20 | 0.31 |
| ▸ | KYAT1 | Q16773 | 1/20 | 0.31 |
| ▸ | KYAT3 | Q6YP21 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 2/20 | 0.31 |
| ▸ | MMP2 | P08253 | 2/20 | 0.31 |
| ▸ | MMP3 | P08254 | 2/20 | 0.31 |
| ▸ | MMP9 | P14780 | 2/20 | 0.31 |
| ▸ | MMP8 | P22894 | 2/20 | 0.31 |
| ▸ | MMP12 | P39900 | 2/20 | 0.31 |
| ▸ | MMP13 | P45452 | 2/20 | 0.31 |
| ▸ | MMP14 | P50281 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569954 | 1.00 | DPP4 (0.35) | DPP4DPP8DPP9AADATMAPT | |
| SCHEMBL9674493 | 0.78 | MEN1 (0.32) | KMT2AMEN1MME | |
| SCHEMBL4216173 | 0.76 | METAP1 (0.42) | DPP4DPP8DPP9KMT2AMEN1 | |
| SCHEMBL5881899 | 0.74 | APEX1 (0.33) | AADATMAPTGOT1KYAT1KYAT3 | |
| SCHEMBL1518987 | 0.74 | ADAM17 (0.32) | MAPTADAM17 | |
| SCHEMBL31396455 | 0.71 | ALDH1A1 (0.33) | — | |
| SCHEMBL1408376 | 0.71 | MAPT (0.35) | MAPTKMT2AMEN1ACE | |
| SCHEMBL7503088 | 0.71 | KMT2A (0.39) | MAPTKMT2A | |
| SCHEMBL31235575 | 0.70 | MT-CO2 (0.33) | AADATKMT2A | |
| SCHEMBL1741998 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871628-A1 | QUINOLIZINONE TYPE COMPOUNDS | Abbott Laboratories (US) | 1998-10-21 | — | — | EP | disclosed |
| WO-1996039407-A1 | QUINOLIZINONE TYPE COMPOUNDS | ABBOTT LABORATORIES (US) | 1996-12-12 | — | — | WO | disclosed |