SCHEMBL17420159

SCHEMBL17420159

CC(C)(C)c1ccc(S(OS(=O)(=O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)(c2cccc3ccccc23)c2cccc3ccccc23)cc1

nearest known ligand 0.41

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RORA P35398 2/20 0.41
RORC P51449 1/20 0.41
NR1H2 P55055 1/20 0.41
NR1H4 Q96RI1 1/20 0.41
NLRP3 Q96P20 1/20 0.40
HSD17B2 P37059 1/20 0.40
HSD11B1 P28845 8/20 0.37
HTR6 P50406 2/20 0.36
CA1 P00915 3/20 0.35
CA2 P00918 3/20 0.35
CA9 Q16790 1/20 0.35
HSP90AA1 P07900 1/20 0.34
HSP90AB1 P08238 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL270056 0.89 RORA (0.40) RORARORCNR1H2NR1H4HTR6
SCHEMBL3680642 0.87 RORA (0.40) RORARORCNR1H2NR1H4HTR6
SCHEMBL3139801 0.86 RORA (0.39) RORARORCNR1H2NR1H4HTR6
SCHEMBL3127145 0.86 RORA (0.39) RORARORCNR1H2NR1H4HTR6
SCHEMBL1593372 0.86 RORA (0.41) RORARORCNR1H2NR1H4HSD11B1
SCHEMBL8515043 0.85 ENPP1 (0.39) RORAHSD17B2HSD11B1CA1CA2
SCHEMBL3139776 0.84 HSD11B1 (0.47) RORANR1H2HSD11B1CA1CA2
SCHEMBL384050 0.84 HSD11B1 (0.47) RORANR1H2HSD11B1CA1CA2
SCHEMBL51946 0.84 CA1 (0.43) RORAHSD11B1CA1CA2CA9
SCHEMBL3135858 0.83 HSD11B1 (0.46) RORANR1H2HSD11B1CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9354523-B2 Composition for resist pattern-refinement, and fine pattern-forming method JSR CORPORATION (JP) 2016-05-31 US disclosed
US-20160011513-A1 COMPOSITION FOR FORMING FINE RESIST PATTERN, AND FINE PATTERN-FORMING METHOD JSR CORPORATION (JP) 2016-01-14 US disclosed