Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 8/20 | 0.43 |
| ▸ | PRKCG | P05129 | 2/20 | 0.39 |
| ▸ | PRKCB | P05771 | 1/20 | 0.39 |
| ▸ | PRKCA | P17252 | 1/20 | 0.39 |
| ▸ | PRKCH | P24723 | 1/20 | 0.39 |
| ▸ | PRKCE | Q02156 | 1/20 | 0.39 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.39 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.39 |
| ▸ | CAMK2B | Q13554 | 1/20 | 0.39 |
| ▸ | CAMK2G | Q13555 | 1/20 | 0.39 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.39 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15910593 | 0.89 | ALDH1A1 (0.38) | ALDH1A1TDP1MEN1MAPTKMT2A | |
| SCHEMBL15910562 | 0.85 | MEN1 (0.38) | ALDH1A1TDP1MEN1KMT2ADDB1 | |
| SCHEMBL8583731 | 0.81 | HTR6 (0.43) | HTR6PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL25939067 | 0.80 | DRD2 (0.43) | HTR6PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL15910903 | 0.78 | LOXL2 (0.47) | ALDH1A1TDP1MEN1MAPTKMT2A | |
| SCHEMBL15910760 | 0.76 | LOXL2 (0.39) | DDB1CRBNHTR3ALCKKDR | |
| SCHEMBL15910759 | 0.76 | LOXL2 (0.39) | DDB1CRBNHTR3ALCKKDR | |
| SCHEMBL30098886 | 0.76 | OPRL1 (0.40) | ALDH1A1HPGD | |
| SCHEMBL1239171 | 0.73 | DRD2 (0.55) | HTR6PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL30588460 | 0.73 | DRD2 (0.55) | HTR6PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3166924-A1 | AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | Sunshine Lake Pharma Co., Ltd. (CN) | 2017-05-17 | — | — | EP | disclosed |
| WO-2016004882-A1 | AROMATIC HETEROCYCLIC DERIVATIVES AND PHARMACEUTICAL APPLICATIONS THEREOF | SUNSHINE LAKE PHARMA CO., LTD. (CN) | 2016-01-14 | — | — | WO | disclosed |