Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHOC | P08134 | 1/20 | 0.46 |
| ▸ | RHOA | P61586 | 1/20 | 0.46 |
| ▸ | TEAD1 | P28347 | 5/20 | 0.42 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 9/20 | 0.41 |
| ▸ | MLNR | O43193 | 1/20 | 0.41 |
| ▸ | PHGDH | O43175 | 1/20 | 0.40 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21856317 | 0.78 | IDH2 (0.43) | TEAD1EPHX2MLNRPHGDH | |
| SCHEMBL2727460 | 0.74 | MEN1 (0.47) | RHOCRHOATEAD1CCR5EPHX2 | |
| SCHEMBL6125248 | 0.74 | POLB (0.63) | RHOCRHOACCR5EPHX2MLNR | |
| SCHEMBL5544096 | 0.74 | RHOC (0.60) | RHOCRHOATEAD1CCR5EPHX2 | |
| SCHEMBL15740363 | 0.73 | CA2 (0.49) | — | |
| SCHEMBL14562834 | 0.72 | RHOC (0.58) | RHOCRHOATEAD1CCR5EPHX2 | |
| SCHEMBL22719543 | 0.72 | TEAD1 (0.70) | RHOCRHOATEAD1CCR5EPHX2 | |
| SCHEMBL21856340 | 0.72 | MALT1 (0.43) | TEAD1EPHX2MLNR | |
| SCHEMBL4239228 | 0.72 | UBE2M (0.45) | RHOCRHOATEAD1CCR5EPHX2 | |
| SCHEMBL21856333 | 0.72 | PHGDH (0.46) | TEAD1EPHX2MLNRPHGDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3177291-A1 | USE OF ANTHELMINTIC AGENTS AGAINST DIROFILARIA IMMITIS | Intervet International B.V. (NL) | 2017-06-14 | — | — | EP | disclosed |
| WO-2016005576-A1 | USE OF ANTHELMINTIC AGENTS AGAINST DIROFILARIA IMMITIS | INTERVET INTERNATIONAL B.V. (NL) | 2016-01-14 | — | — | WO | disclosed |