⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25168054 | 0.80 | CYP3A4 (0.35) | — | |
| SCHEMBL17423953 | 0.76 | JAK2 (0.36) | — | |
| SCHEMBL31207146 | 0.74 | RXFP1 (0.41) | — | |
| SCHEMBL31753982 | 0.72 | EGFR (0.36) | — | |
| SCHEMBL19087000 | 0.71 | CSF1R (0.34) | — | |
| SCHEMBL22320285 | 0.71 | ACHE (0.33) | — | |
| SCHEMBL25064941 | 0.71 | P2RX7 (0.33) | — | |
| SCHEMBL25064944 | 0.71 | P2RX7 (0.33) | — | |
| SCHEMBL25065570 | 0.71 | P2RX7 (0.33) | — | |
| SCHEMBL28544224 | 0.71 | CA1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230020922-A1 | METHODS AND COMPOSITIONS FOR MODULATING SPLICING | SKYHAWK THERAPEUTICS, INC. | 2023-01-19 | — | — | US | disclosed |