Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 3/20 | 0.43 |
| ▸ | NPY1R | P25929 | 3/20 | 0.43 |
| ▸ | NPY4R | P50391 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | KISS1R | Q969F8 | 3/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.42 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.42 |
| ▸ | FURIN | P09958 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.40 |
| ▸ | CHRNG | P07510 | 1/20 | 0.40 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.40 |
| ▸ | CHRND | Q07001 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12035482 | 0.90 | NPY4R (0.54) | NPY5RNPY1RNPY4RCTSLKISS1R | |
| SCHEMBL17424430 | 0.85 | KISS1R (0.47) | NPY5RNPY1RNPY4RKISS1RGRIN1 | |
| SCHEMBL17424377 | 0.84 | KISS1R (0.57) | NPY5RNPY1RNPY4RKISS1RFURIN | |
| SCHEMBL7449318 | 0.82 | POLB (0.54) | POLBCNR2 | |
| SCHEMBL17424417 | 0.82 | CA1 (0.46) | NPY5RNPY1RNPY4RKISS1RFURIN | |
| SCHEMBL17424378 | 0.82 | KISS1R (0.57) | NPY5RNPY1RNPY4RKISS1RFURIN | |
| SCHEMBL17424441 | 0.82 | NPY5R (0.42) | NPY5RNPY1RNPY4RFURIN | |
| SCHEMBL17424409 | 0.81 | NPY4R (0.40) | NPY5RNPY1RNPY4RFURINSIRT2 | |
| SCHEMBL17424420 | 0.81 | NPY5R (0.43) | NPY5RNPY1RNPY4RCTSLKISS1R | |
| SCHEMBL17424369 | 0.80 | SIRT5 (0.44) | NPY5RNPY1RNPY4RKISS1RFURIN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233086-B2 | Inhibition of WDR5 interaction with its binding partners | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-01-12 | — | — | US | disclosed |