Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KISS1R | Q969F8 | 4/20 | 0.47 |
| ▸ | PADI1 | Q9ULC6 | 4/20 | 0.43 |
| ▸ | PADI4 | Q9UM07 | 4/20 | 0.43 |
| ▸ | PDE4A | P27815 | 3/20 | 0.43 |
| ▸ | PADI2 | Q9Y2J8 | 3/20 | 0.43 |
| ▸ | PADI3 | Q9ULW8 | 3/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.43 |
| ▸ | PADI6 | Q6TGC4 | 1/20 | 0.43 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.41 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.41 |
| ▸ | NPY1R | P25929 | 3/20 | 0.41 |
| ▸ | NPY4R | P50391 | 2/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12035478 | 0.89 | NPY4R (0.51) | KISS1RPADI1PADI4PDE4APADI2 | |
| SCHEMBL17424445 | 0.85 | NPY5R (0.43) | KISS1RGRIN1GRIN2ANPY5RNPY1R | |
| SCHEMBL17424409 | 0.83 | NPY4R (0.40) | NPY5RNPY1RNPY4R | |
| SCHEMBL17424369 | 0.82 | SIRT5 (0.44) | KISS1RNPY5RNPY1RNPY4R | |
| SCHEMBL17424377 | 0.81 | KISS1R (0.57) | KISS1RNPY5RNPY1RNPY4R | |
| SCHEMBL17424416 | 0.80 | SIRT1 (0.45) | KISS1RSMN1; SMN2 | |
| SCHEMBL17424438 | 0.80 | NPY1R (0.42) | KISS1RNPY5RNPY1RNPY4RSMN1; SMN2 | |
| SCHEMBL17424422 | 0.80 | NPY4R (0.38) | KISS1RNPY5RNPY1RNPY4R | |
| SCHEMBL17424417 | 0.79 | CA1 (0.46) | KISS1RPADI4NPY5RNPY1RNPY4R | |
| SCHEMBL17424378 | 0.79 | KISS1R (0.57) | KISS1RNPY5RNPY1RNPY4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9233086-B2 | Inhibition of WDR5 interaction with its binding partners | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2016-01-12 | — | — | US | disclosed |