Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB1 | P20618 | 10/20 | 0.53 |
| ▸ | PSMB5 | P28074 | 10/20 | 0.53 |
| ▸ | PSMB9 | P28065 | 9/20 | 0.53 |
| ▸ | PSMB8 | P28062 | 9/20 | 0.53 |
| ▸ | PSMB10 | P40306 | 4/20 | 0.53 |
| ▸ | PSMB2 | P49721 | 4/20 | 0.53 |
| ▸ | BCL2 | P10415 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 5/20 | 0.47 |
| ▸ | CTSK | P43235 | 3/20 | 0.47 |
| ▸ | CTSB | P07858 | 2/20 | 0.47 |
| ▸ | CTSL | P07711 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1353726 | 0.93 | PSMB1 (0.54) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL19190193 | 0.91 | PSMB1 (0.51) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL1349239 | 0.91 | PSMB1 (0.51) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL8523666 | 0.84 | CTSS (0.52) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL19190003 | 0.84 | BCL2 (0.52) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL1350878 | 0.83 | PTPN1 (0.57) | BCL2CTSSCTSKCTSBCTSL | |
| SCHEMBL1350409 | 0.83 | PTPN1 (0.57) | BCL2CTSSCTSKCTSBCTSL | |
| SCHEMBL8474091 | 0.81 | BCL2 (0.50) | PSMB1PSMB5PSMB9PSMB8BCL2 | |
| SCHEMBL993498 | 0.80 | CTSS (0.59) | PSMB1PSMB5PSMB9PSMB8PSMB10 | |
| SCHEMBL7366740 | 0.80 | PSMB1 (0.62) | PSMB1PSMB5PSMB9PSMB8PSMB10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2388247-B1 | Histone deacetylase inhibitors | UNIV TAIPEI MEDICAL (TW) | 2017-08-02 | — | — | EP | disclosed |
| US-8242282-B2 | Histone deacetylase inhibitors | TAIPEI MEDICAL UNIVERSITY (TW) | 2012-08-14 | — | — | US | disclosed |
| US-20110288133-A1 | HISTONE DEACETYLASE INHIBITORS | TAIPEI MEDICAL UNIVERSITY (TW) | 2011-11-24 | — | — | US | disclosed |
| EP-2388247-A2 | Histone deacetylase inhibitors | Taipei Medical University (TW) | 2011-11-23 | — | — | EP | disclosed |
| US-8039296-B2 | Organic thin film transistor array panel and manufacturing method thereof | SAMSUNG ELECTRONICS CO., LTD. (KR) | 2011-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288133-A1 | HISTONE DEACETYLASE INHIBITORS | HDAC1, HDAC5, HDAC2 | PSMB1 1819/4885PSMB5 981/4885PSMB9 1811/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.