Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 4/20 | 0.49 |
| ▸ | CA2 | P00918 | 4/20 | 0.49 |
| ▸ | CA9 | Q16790 | 4/20 | 0.49 |
| ▸ | CA12 | O43570 | 3/20 | 0.49 |
| ▸ | CA7 | P43166 | 3/20 | 0.49 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | TOP2A | P11388 | 1/20 | 0.40 |
| ▸ | PTPRC | P08575 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1033944 | 0.83 | KDM4E (0.47) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL667702 | 0.83 | ALDH1A1 (0.47) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL6420919 | 0.83 | ALDH1A1 (0.47) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL17424942 | 0.80 | ALDH1A1 (0.48) | TSHRLMNACA1CA2CA9 | |
| SCHEMBL2655486 | 0.80 | LMNA (0.61) | TSHRLMNACA1CA2CA9 | |
| SCHEMBL17424944 | 0.79 | LMNA (0.59) | TSHRLMNACA1CA2CA9 | |
| SCHEMBL18396554 | 0.79 | ALDH1A1 (0.54) | TSHRLMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL15110844 | 0.78 | LMNA (0.58) | TSHRLMNACA1CA2CA9 | |
| SCHEMBL13851543 | 0.76 | LMNA (0.56) | TSHRLMNACA1CA2CA9 | |
| SCHEMBL2427784 | 0.76 | ALDH1A1 (0.57) | TSHRLMNAKDM4EALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2463269-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-09-28 | — | — | EP | disclosed |
| EP-2460786-B1 | Bioavailable diacylhydrazine ligands for modulating the expression of exogenous genes via an ecdysone receptor complex | INTREXON CORP (US) | 2016-01-13 | — | — | EP | disclosed |