Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CFTR | P13569 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | NOX4 | Q9NPH5 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29548152 | 1.00 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4EHSD17B10POLB | |
| SCHEMBL7276972 | 0.84 | ALDH1A1 (0.58) | ALDH1A1LMNAKDM4EHSD17B10POLB | |
| SCHEMBL4324495 | 0.84 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EHSD17B10POLB | |
| SCHEMBL4968519 | 0.84 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EHSD17B10POLB | |
| SCHEMBL2192561 | 0.84 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EHSD17B10POLB | |
| SCHEMBL21958010 | 0.83 | ALDH1A1 (0.62) | ALDH1A1LMNAKDM4EHSD17B10POLB | |
| SCHEMBL11247916 | 0.83 | TSHR (0.62) | ALDH1A1LMNAKDM4EHSD17B10TSHR | |
| SCHEMBL4672146 | 0.83 | ALDH1A1 (0.57) | ALDH1A1LMNAKDM4EHSD17B10POLB | |
| SCHEMBL6965125 | 0.80 | ALDH1A1 (0.62) | ALDH1A1LMNAKDM4EHSD17B10POLB | |
| SCHEMBL5487519 | 0.80 | KMT2A (0.47) | ALDH1A1LMNAKDM4EHSD17B10CFTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 229 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-3099077-A | — | — | None | — | — | JP | disclosed |
| US-20260062425-A1 | AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2026-03-05 | — | — | US | disclosed |
| US-12473280-B2 | Substituted tricyclic compound as PRMT5 inhibitor and use thereof | NANJING SANHOME PHARMACEUTICAL CO., LTD. (CN) | 2025-11-18 | — | — | US | disclosed |
| US-12338256-B2 | Aza-tetracyclic oxazepine compounds and uses thereof | GENENTECH, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| EP-4526309-A1 | AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | Genentech, Inc. (US) | 2025-03-26 | — | — | EP | disclosed |
| CN-119306629-A | Preparation method of m-cyanomethyl benzoate | 甘肃汉隆化工有限公司 | 2025-01-14 | — | — | CN | disclosed |
| US-20240368186-A1 | AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2024-11-07 | — | — | US | disclosed |
| WO-2024120360-A1 | PARP7 INHIBITOR, PREPARATION METHOD THEREFOR AND USE THEREOF | 成都先导药物开发股份有限公司 | 2024-06-13 | — | — | WO | disclosed |
| CN-112334465-B | Tricyclic substituted oxaspiro derivatives, preparation and pharmaceutical use thereof | 上海海雁医药科技有限公司 | 2024-06-11 | — | — | CN | disclosed |
| CN-118146212-A | PARP7 inhibitor and preparation method and application thereof | 成都先导药物开发股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| WO-1999065904-A1 | TRIAZOLO-PYRIDINE DERIVATIVES AS LIGANDS FOR GABA RECEPTORS | MERCK SHARP & DOHME LIMITED (GB) | 1999-12-23 | — | — | WO | disclosed |
| EP-0416820-B1 | Novel compounds exhibiting a vasodilating activity and inhibitory activity for platelet aggregation and pharmaceutical compositions containing them | HIDAKA HIROYOSHI (JP) | 1994-08-03 | — | — | EP | disclosed |
| US-5059692-A | NOVEL COMPOUNDS EXHIBITING A VASODILATING ACTIVITY AND INHIBITORY ACTIVITY FOR PLATELET AGGREGATION | HIDAKA HIROYOSHI (JP) | 1991-10-22 | — | — | US | disclosed |
| WO-1991010653-A1 | HERBICIDAL PYRIMIDINES AND TRIAZINES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-07-25 | — | — | WO | disclosed |
| JP-H0399077-A | TETRASUBSTITUTED THIOPHENE AND ITS PRODUCTION | HIDAKA HIROYOSHI | 1991-04-24 | — | — | JP | disclosed |
| EP-0416820-A2 | Novel compounds exhibiting a vasodilating activity and inhibitory activity for platelet aggregation and pharmaceutical compositions containing them | Hidaka, Hiroyoshi (JP) | 1991-03-13 | — | — | EP | disclosed |
| US-4873254-A | ADRENERGIC BLOCKING AGENTS OR CALCIUM CHANNEL BLOCKERS; HYPOTENSIVE AGENTS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-10-10 | — | — | US | disclosed |
| EP-0194751-A1 | Dihydropyridine alkanol amines, process for their preparation and pharmaceutical compositions containing them | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1986-09-17 | — | — | EP | disclosed |
| US-4337256-A | ANTIINFLAMMATORY AGENTS; ANTIAGGLOMERANTS; ENZYME INHIBITORS; ANTIULCER AGENTS | TEIKOKU HORMONE MANUFACTURING CO., LTD. (JP) | 1982-06-29 | — | — | US | disclosed |
| EP-0013411-A1 | Isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | TEIKOKU HORMONE MFG. CO., LTD. (JP) | 1980-07-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12473280-B2 | Substituted tricyclic compound as PRMT5 inhibitor and use thereof | PRMT5, PRMT1, PRMT8 | ALDH1A1 4153/4885LMNA 2398/4885KDM4E 71/4885 |
| US-12338256-B2 | Aza-tetracyclic oxazepine compounds and uses thereof | AZI2, TET3, OXA1L | ALDH1A1 1000/4885LMNA 4245/4885KDM4E 553/4885 |
| US-20260062425-A1 | AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | KRAS, NRAS, HRAS | ALDH1A1 908/4885LMNA 3592/4885KDM4E 981/4885 |
| US-20240368186-A1 | AZA-TETRACYCLIC OXAZEPINE COMPOUNDS AND USES THEREOF | AZI2, TET3, OXA1L | ALDH1A1 1000/4885LMNA 4245/4885KDM4E 553/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.