Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | PNKP | Q96T60 | 2/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.32 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11899734 | 0.81 | LMNA (0.35) | MAPTALDH1A1LMNASMN1; SMN2PNKP | |
| SCHEMBL21159495 | 0.79 | CHRM2 (0.39) | MAPTALDH1A1LMNASMN1; SMN2HCAR3 | |
| SCHEMBL12138409 | 0.69 | ALDH1A1 (0.44) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL2552457 | 0.69 | ALDH1A1 (0.50) | MAPTALDH1A1LMNASMN1; SMN2HTT | |
| SCHEMBL1742856 | 0.68 | MAPT (0.39) | MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL1742858 | 0.68 | MAPT (0.39) | MAPTALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL20840383 | 0.68 | PTGS1 (0.44) | — | |
| SCHEMBL10891917 | 0.67 | MAPT (0.44) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL8598011 | 0.66 | MAPT (0.49) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 | |
| SCHEMBL10891895 | 0.66 | HCAR3 (0.48) | MAPTALDH1A1LMNASMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389436-A2 | STEM CELL CULTURE METHODS | ITI Scotland Limited (GB) | 2011-11-30 | — | — | EP | disclosed |
| US-20110257911-A1 | SYSTEMS AND METHODS FOR DETECTING CHANGES IN ENERGY USAGE IN A BUILDING | JOHNSON CONTROLS TECHNOLOGY COMPANY | 2011-10-20 | — | — | US | disclosed |
| WO-2010084300-A2 | STEM CELL CULTURE METHODS | ITI SCOTLAND LIMITED (GB) | 2010-07-29 | — | — | WO | disclosed |