Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | NQO2 | P16083 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11899734 | 0.85 | LMNA (0.35) | MAPTLMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL7885090 | 0.80 | LMNA (0.41) | CYP2C19NR4A2MAPTLMNAALDH1A1 | |
| SCHEMBL1742733 | 0.79 | MAPT (0.35) | MAPTLMNAALDH1A1SMN1; SMN2HCAR3 | |
| SCHEMBL7720730 | 0.75 | ALDH1A1 (0.36) | MAPTKDM4ELMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL28908267 | 0.74 | LMNA (0.38) | CYP2D6CYP2C19TDP1NR4A2MAPT | |
| SCHEMBL7034302 | 0.73 | IDH1 (0.38) | MAPTLMNAIDO1ALDH1A1SMN1; SMN2 | |
| SCHEMBL12138409 | 0.72 | ALDH1A1 (0.44) | TDP1MAPTKDM4EHSD17B10LMNA | |
| SCHEMBL29744939 | 0.71 | HCAR3 (0.45) | TDP1MAPTLMNAIDO1ALDH1A1 | |
| SCHEMBL20840383 | 0.71 | PTGS1 (0.44) | CYP2C19KDM4E | |
| SCHEMBL29745027 | 0.70 | HCAR3 (0.44) | TDP1MAPTLMNAIDO1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3505171-A1 | BICYCLIC NITROGENATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2019-07-03 | — | — | EP | disclosed |