Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.31 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 2/20 | 0.30 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.30 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.30 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.30 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17428191 | 0.92 | TAS1R3 (0.31) | RIPK1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL17428204 | 0.92 | AXL (0.33) | AXLRIPK1SHBG | |
| SCHEMBL17428195 | 0.91 | RIPK1 (0.34) | AXLRIPK1SHBGKLKB1 | |
| SCHEMBL17428158 | 0.90 | AXL (0.31) | AXL | |
| SCHEMBL17428199 | 0.89 | RIPK1 (0.33) | AXLRIPK1HCRTR1LTC4SSHBG | |
| SCHEMBL16864940 | 0.88 | AXL (0.32) | AXLRIPK1HCRTR1LTC4S | |
| SCHEMBL17428157 | 0.88 | AXL (0.30) | AXLRIPK1 | |
| SCHEMBL17428179 | 0.88 | NPC1 (0.32) | MEN1KMT2ATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL17428171 | 0.87 | NAAA (0.32) | LMNATAS1R3TAS1R1TAS1R2 | |
| SCHEMBL16864939 | 0.86 | AXL (0.31) | AXLRIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9955691-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-9955691-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160007601-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2016-01-14 | — | — | US | disclosed |
| US-20160007601-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2016-01-14 | — | — | US | disclosed |
| WO-2016007529-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160007601-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, FKBP2 | AXL 2819/4885RIPK1 4127/4885HCRTR1 375/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.