Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.34 |
| ▸ | RELA | Q04206 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | REN | P00797 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17428250 | 0.99 | GAA (0.42) | GAANAAANFKB1NFKB2RELA | |
| SCHEMBL17428270 | 0.84 | KMT2A (0.41) | GAANAAAKMT2AL3MBTL1 | |
| SCHEMBL17428280 | 0.82 | GAA (0.37) | GAAKMT2AL3MBTL1 | |
| SCHEMBL17898651 | 0.81 | NAAA (0.40) | GAANAAANFKB1NFKB2RELA | |
| SCHEMBL17428281 | 0.79 | KDM1A (0.41) | GAAKMT2AL3MBTL1 | |
| SCHEMBL17428283 | 0.79 | GAA (0.47) | GAANAAANFKB1NFKB2RELA | |
| SCHEMBL17898650 | 0.79 | NAAA (0.39) | GAANAAANFKB1NFKB2RELA | |
| SCHEMBL15366902 | 0.76 | GAA (0.42) | GAANFKB1NFKB2RELABTK | |
| SCHEMBL19089218 | 0.76 | GAA (0.46) | GAANAAANFKB1NFKB2RELA | |
| SCHEMBL17898717 | 0.76 | NAAA (0.39) | GAANAAANFKB1NFKB2RELA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9955691-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-9955691-B2 | Macrocyclic picolinamides as fungicides | DOW AGROSCIENCES LLC (US) | 2018-05-01 | — | — | US | disclosed |
| US-20160007601-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2016-01-14 | — | — | US | disclosed |
| US-20160007601-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC | 2016-01-14 | — | — | US | disclosed |
| WO-2016007529-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | DOW AGROSCIENCES LLC (US) | 2016-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160007601-A1 | MACROCYCLIC PICOLINAMIDES AS FUNGICIDES | CYP4F12, CYP1A2, FKBP2 | GAA 1303/4885NAAA 2646/4885NFKB1 4561/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.