Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HB | P07237 | 1/20 | 0.46 |
| ▸ | CCR6 | P51684 | 1/20 | 0.45 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.45 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.45 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.43 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17386083 | 0.92 | P4HB (0.43) | P4HBCCR6HKDC1NOTUMCYP4A11 | |
| SCHEMBL17429642 | 0.89 | CYP4A11 (0.52) | P4HBCCR6HKDC1NOTUMCYP4A11 | |
| SCHEMBL17386069 | 0.80 | HDAC1 (0.53) | P4HBCYP4A11CYP4F2CA1CA2 | |
| SCHEMBL17385775 | 0.79 | NPC1 (0.56) | P4HBCCR6HKDC1NOTUMCYP4A11 | |
| SCHEMBL27594634 | 0.79 | NOTUM (0.53) | P4HBCCR6HKDC1NOTUMCYP4A11 | |
| SCHEMBL17429671 | 0.78 | KDM4E (0.44) | CCR6HKDC1NOTUMKDM4EALDH1A1 | |
| SCHEMBL21205721 | 0.77 | NOTUM (0.51) | P4HBCCR6HKDC1NOTUMCYP4A11 | |
| SCHEMBL17429703 | 0.77 | P4HB (0.45) | P4HBCCR6HKDC1NOTUMCYP4A11 | |
| SCHEMBL3577577 | 0.77 | NOTUM (0.57) | P4HBCCR6HKDC1NOTUMMAPK10 | |
| SCHEMBL17429651 | 0.77 | CYP4A11 (0.38) | CYP4A11CYP4F2KDM4EALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9643946-B2 | Tricyclic compound and use thereof | SK CHEMICALS CO., LTD. (KR) | 2017-05-09 | — | — | US | disclosed |
| US-20160009677-A1 | TRICYCLIC COMPOUND AND USE THEREOF | SK CHEMICALS CO., LTD. (KR) | 2016-01-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160009677-A1 | TRICYCLIC COMPOUND AND USE THEREOF | GPR65, GPR119, GPR35 | P4HB 4077/4885CCR6 473/4885HKDC1 782/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.